Anticholinergic / barbiturate combinations are used to treat irritable bowel syndrome (IBS), stomach ulcers, and inflammation in the digestive tract. These medications work by combining the effects of anticholinergics, which reduce muscle spasms and secretions in the digestive tract, and barbiturates, which have a calming effect on the nervous system. These combinations are available in different forms, including oral tablets and elixirs. Examples include phenobarbital / hyoscyamine / atropine / scopolamine (Donnatal, Phenohytro). Your prescriber can help you choose the form that best fits your needs.