The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Sleepiness (27%)
- Weight gain (25%)
- Large appetite (20%)
- Dry mouth (15%)
- Swelling from fluids (15%)
- Tiredness (12%)
- Shakiness (9%)
Note: Side effects listed were reported by adults in clinical studies.
Less Common Side Effects
- Blurry vision
- Weakness
- Pain
- Having a hard time paying attention
- Feeling restless
- Sexual dysfunction
- Nervousness
- Fever
- Runny nose
Symbyax serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Suicidal thoughts or actions
- Serious allergic and skin reactions: hives, blisters, skin reddening or peeling, swelling of the lips or tongue, difficulty breathing
- Neuroleptic malignant syndrome: fever, sweating, stiff muscles, confusion, not aware of your surroundings, fast or irregular heartbeat
- Serotonin syndrome: fast heart rate, dizziness, sweating, flushing, tremor (shakiness), muscle stiffness, muscle twitching or spasms, uncoordinated movement, distress, seizures, distress, hallucinations, coma
- Difficulty swallowing
- Seizures
- Abnormal heart rhythm (QT prolongation): chest pounding, short of breath, chest pain, feeling faint or lightheaded
- Dangerously high blood sugar: frequently thirsty, needing to urinate often, tiredness, nausea, vomiting, difficulty breathing, having fruity breath, having dry mouth
- Low blood sodium levels: nausea, fatigue, headache, confusion, disoriented, hallucinations (seeing things that aren't real), seizures, unconsciousness
Source: DailyMed
The following Symbyax side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
Bloating or swelling of the face, arms, hands, lower legs, or feet
body aches or pain
confusion
congestion
delusions
dryness or soreness of the throat
hoarseness
rapid weight gain
shakiness in the legs, arms, hands, or feet
tender, swollen glands in the neck
tingling of the hands or feet
trembling or shaking of the hands or feet
trouble with swallowing
unusual weight gain or loss
voice changes
Less common
Blurred vision
change in personality
change in vision
difficult or labored breathing
difficulty with sleeping
difficulty with speaking
dizziness
ear pain
headache
impaired vision
increase in body movements
loss of memory
nervousness
pounding in the ears
problems with memory
slow, fast, pounding, or irregular heartbeat or pulse
tightness in the chest
Rare
Inability to move the eyes
increased blinking or spasms of the eyelid
sticking out of the tongue
uncontrolled twisting movements of the neck, trunk, arms, or legs
unusual facial expressions
Incidence not known
Bloody or black, tarry stools
severe stomach pain
vomiting of blood or material that looks like coffee grounds
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common
Change or problem with discharge of semen
decreased interest in sexual intercourse
difficulty with moving
inability to have or keep an erection
loss in sexual ability, desire, drive, or performance
muscle pain or stiffness
not able to have an orgasm
pain, swelling, or redness in the joints
tooth disorder
twitching
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
