Opioids are used to treat pain, opioid dependence, and diarrhea. They work by affecting areas of the brain that sense pain and by allowing more fluid to be absorbed in the small intestine.

Why are
Opioids
prescribed?

How is this chart calculated?

How we make this chart

This chart is created by aggregating the total number of claims for the drugs in this class divided by the # of drugs with a specific indication. It is meant to be representative but may not accurately reflect the actual # of prescriptions written to treat a specific condition.

Prices for Popular Opioids

Popularity Brand Name (Generic Name) GoodRx Fair Price Price Trend
Ultram
(tramadol)
8
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Tramadol (Ultram) is an inexpensive drug used to treat moderate to severe pain in adults. This drug is more popular than comparable drugs. It is available in generic and brand versions. Generic tramadol is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Roxicodone
(oxycodone)
17
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Oxycodone (Roxicodone) is a moderately priced drug used to treat moderate to severe pain. This drug is slightly more popular than comparable drugs. It is available in both generic and brand versions. Generic oxycodone is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Kadian
(morphine er)
27
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MORPHINE is a pain reliever. It is used to treat moderate to severe pain that lasts for more than a few days.
MS Contin
(morphine er)
27
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MORPHINE is a pain reliever. It is used to treat moderate to severe pain that lasts for more than a few days.
Oxycontin
(oxycodone er)
140
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OXYCODONE is a pain reliever. It is used to treat constant pain that lasts for more than a few days.
Dilaudid
(hydromorphone)
8
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HYDROMORPHONE is a pain reliever. It is used to treat moderate to severe pain.
Methadose
(methadone)
22
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METHADONE is a pain reliever. It is used to treat severe pain. The medicine is also used to prevent withdrawal symptoms in people addicted to other drugs.
Dolophine
(methadone)
22
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METHADONE is a pain reliever. It is used to treat severe pain. The medicine is also used to prevent withdrawal symptoms in people addicted to other drugs.
Duragesic
(fentanyl)
50
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FENTANYL is a pain reliever. It is used to treat persistent, moderate to severe chronic pain. It is used only by people who have been taking an opioid or narcotic pain medicine for more than one week.
morphine
21
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MORPHINE is a pain reliever. It is used to treat moderate to severe pain.
Conzip
(tramadol er)
52
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TRAMADOL is a pain reliever. It is used to treat moderate to severe pain in adults.
Ultram ER
(tramadol er)
52
See Prices
TRAMADOL is a pain reliever. It is used to treat moderate to severe pain in adults.
oxymorphone ER
363
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OXYMORPHINE is a pain reliever. It is used to treat moderate to severe pain that lasts for more than a few days. It is used by people who have been taking an opioid or narcotic pain medicine.
Nucynta
297
See Prices
Nucynta (tapentadol) is an opioid used to relieve short term moderate to severe pain. Tapentadol is a controlled substance and a new prescription must be obtained for each fill. There is no generic version of Nucynta available, but there is a twice-daily extended release option, Nucynta ER.
Nucynta ER
584
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Nucynta ER (tapentadol) is an opioid used to relieve short term moderate to severe pain. It is the extended-release version of Nucynta, and may be taken twice daily instead of every four to six hours. Tapentadol is a controlled substance and a new prescription must be obtained for each fill. There is no generic version of Nucynta ER available.
Opana
(oxymorphone)
121
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Oxymorphone (Opana) is an expensive drug used to treat moderate to severe pain. This drug is less popular than comparable drugs. It is available in brand and generic versions. Generic oxymorphone is covered by some Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Opana ER
292
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OXYMORPHINE is a pain reliever. It is used to treat moderate to severe pain that lasts for more than a few days. It is used by people who have been taking an opioid or narcotic pain medicine.
Demerol
(meperidine)
38
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MEPERIDINE is a pain reliever. It is used to treat moderate to severe pain.
codeine
32
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CODEINE is a pain reliever. It is used to treat mild to moderate pain.
Hysingla ER
224
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HYDROCODONE is a pain reliever. It is used to treat constant pain that lasts for more than a few days.
Exalgo
(hydromorphone er)
294
See Prices
HYDROMORPHONE is a pain reliever. It is used to treat moderate to severe pain. It is used by people who have been taking an opioid or narcotic pain medicine.
opium
396
See Prices
OPIUM TINCTURE (OH-pee-uhm) belongs to the same class of medicines as the narcotic pain relievers. However, this medicine is used to decrease the number and frequency of bowel movements. It is used to treat diarrhea.
Zohydro ER
486
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HYDROCODONE is a pain reliever. It is used to treat constant pain that lasts for more than a few days.
morphine once-daily
249
See Prices
MORPHINE is a pain reliever. It is used to treat moderate to severe pain that lasts for more than a few days. It is used by people who have been taking an opioid or narcotic pain medicine.
Actiq
(fentanyl citrate)
682
See Prices
FENTANYL is a pain reliever. It is used to treat breakthrough cancer pain that your long acting pain medicine does not control. Do not use this medicine for a pain that will go away in a few days like pain from surgery, doctor or dentist visits. The medicine is used only by people who have been taking an opioid or narcotic pain medicine for at least a week.
Xtampza ER
390
See Prices
OXYCODONE is a pain reliever. It is used to treat constant pain that lasts for more than a few days.
levorphanol
2,940
See Prices
Levorphanol is a pain reliever. It is used to treat moderate to severe pain.
Subsys
5,577
See Prices
FENTANYL is a pain reliever. It is used to treat breakthrough cancer pain that your long acting pain medicine does not control. Do not use this medicine for a pain that will go away in a few days like pain from surgery, doctor or dentist visits. The medicine is used only by people who have been taking an opioid or narcotic pain medicine for at least a week.
Oxaydo
1,004
See Prices
OXYCODONE is a pain reliever. It is used to treat moderate to severe pain.
Fentora
2,265
See Prices
FENTANYL is a pain reliever. It is used to treat breakthrough cancer pain that your long acting pain medicine does not control. Do not use this medicine for a pain that will go away in a few days like pain from surgery, doctor or dentist visits. The medicine is used only by people who have been taking an opioid or narcotic pain medicine for at least a week.
Probuphine
5,447
See Prices
BUPRENORPHINE is used to treat certain types of drug dependence.
Onsolis
662
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Lazanda
785
See Prices
FENTANYL is a pain reliever. It is used to treat breakthrough cancer pain that your long acting pain medicine does not control. Do not use this medicine for a pain that will go away in a few days like pain from surgery, doctor or dentist visits. The medicine is used only by people who have been taking an opioid or narcotic pain medicine for at least a week.
Ionsys
882
See Prices
Abstral
3,757
See Prices

Note: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

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