Amitiza (lubiprostone) is a laxative used to treat chronic constipation and constipation caused by opioids. Amitiza is the only drug in the chloride channel activators class. There are currently no generic alternatives to Amitiza.
Check our savings tips for co-pay cards, assistance programs, and other ways to reduce your cost. Amitiza is covered by most Medicare and insurance plans.
Lubiprostone Side Effects
What should I watch for?
Visit your doctor for regular check ups. Tell your doctor if your symptoms do not get better or if they get worse.
Common and Rare Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
full or bloated feeling or pressure in the stomach
swelling of the abdominal or stomach area
Black, tarry stools
blood in the stools
chest discomfort or pain
difficult or labored breathing
general feeling of discomfort or illness
loss of appetite
loss of bowel control
muscle aches and pains
tightness in the chest
unusual tiredness or weakness
Incidence not known
difficulty with swallowing
dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
fast, pounding, or irregular heartbeat or pulse
hives or skin rash
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
Get emergency help immediately if any of the following symptoms of overdose occur:
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
bloody or cloudy urine
change in taste
difficult, burning, or painful urination
difficulty with moving
fear or nervousness
feeling sad or empty
frequent urge to urinate
loss of interest or pleasure
loss of taste
lower back or side pain
tingling of the hands or feet
unusual drowsiness, dullness, tiredness, or feeling of sluggishness
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.