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Chloride Channel Activators

Chloride channel activators are used to treat constipation and irritable bowel syndrome. They work by increasing fluid allowing for easier stool passing.

Why are chloride channel activators prescribed?

  1. Constipation (100%)
  2. Irritable Bowel Syndrome (0%)

Key takeaways

Chloride channel activators are used to treat chronic idiopathic constipation, irritable bowel syndrome with constipation, and opioid-induced constipation. These medications work by activating chloride channels in the intestines, which helps increase fluid secretion to soften stool and improve bowel movements. Chloride channel activators are available in oral form. An example is lubiprostone (Amitiza). This medication can help you manage your constipation more effectively.

Prices for popular Chloride Channel Activators medications
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Amitiza (lubiprostone) is a laxative used to treat chronic constipation and constipation caused by opioids. Amitiza is the only drug in the chloride channel activators class. There are currently no generic alternatives to Amitiza.

Check our savings tips for co-pay cards, assistance programs, and other ways to reduce your cost. Amitiza is covered by most Medicare and insurance plans.
Disclaimer: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

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