Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Lactulose (Constulose) and docusate/senna (Senna-S) are both used to treat constipation, but they work differently and have distinct characteristics. Lactulose is an osmotic laxative that draws fluid into the gut to soften stool, and it typically takes 1 to 2 days to work. It is available only by prescription and can be used in people with kidney or liver problems. Common side effects include stomach pain and gas. On the other hand, docusate/senna is a combination of a stool softener and a stimulant laxative, which works by both softening the stool and stimulating the intestines to push it out. It usually works within 6 to 12 hours and is available over-the-counter. Docusate/senna is recommended for short-term use and can cause stomach cramps and loose stools. While lactulose is not a first-choice laxative due to its side effects and slower action, docusate/senna is favored for its quicker relief but should not be used for more than a week without consulting a healthcare professional.
Lactulose (Constulose)
Docusate/senna
Lactulose (Constulose)
Docusate/senna
Summary of Lactulose vs. Senexon-s
Summary for Osmotic laxative
Prescription only
Lactulose (Constulose) is a liquid osmotic laxative. It's used to help relieve constipation in adults. This medication is taken by mouth, typically once daily. Once you start treatment, it can take up to two days before you have a bowel movement. Some common side effects of lactulose (Constulose) include stomach pain and passing gas. There's a separate version of lactulose used for symptoms of a liver problem called hepatic encephalopathy.
Summary for Stool softener / Stimulant laxative
Docusate/senna is a combination medication containing docusate and senna. The two laxatives work together to treat constipation.