Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Senna-S (docusate/senna) and Metamucil (psyllium) are both over-the-counter medications used to treat occasional constipation, but they work in different ways. Senna-S combines a stool softener (docusate) and a stimulant laxative (senna). Docusate draws water into your intestines to soften your stool, while senna stimulates your intestines to help push the stool out. In contrast, Metamucil is a bulk-forming fiber laxative that helps your stool absorb and hold onto water, making it bigger and softer for easier passage. Senna-S typically works within 6 to 12 hours and is often taken at night, while Metamucil can take 12 to 72 hours to relieve constipation and can be taken at any time of the day. Senna-S should be used short-term and can cause stomach cramps and loose stools, whereas Metamucil requires a lot of liquid to prevent choking and can cause bloating. Both medications are available in various forms and do not require a prescription.
Docusate/senna
Psyllium (Metamucil)
Docusate/senna
Psyllium (Metamucil)
Summary of Senexon-s vs. Metamucil
Summary for Stool softener / Stimulant laxative
Docusate/senna is a combination medication containing docusate and senna. The two laxatives work together to treat constipation.
Summary for Fiber laxative
Psyllium or psyllium husk (Metamucil) is an over-the-counter (OTC) fiber supplement that helps with occasional constipation. It can cause choking if you don't take it with enough water or other fluid.
Indications of Senexon-s vs. Metamucil
Indications for
•Occasional constipation
Indications for
•Occasional constipation
Pros and Cons of Senexon-s vs. Metamucil
Pros and Const for Stool softener / Stimulant laxative
Pros
•Contains two medications, so there's fewer pills and can sometimes be cheaper
•Available over-the-counter so you don't need a prescription from your provider
•Works fast to help you have a bowel movement
Cons
•Should only be used short-term (less than 7 days)
•Some people have stomach cramps
•Can cause loose, watery stools
Pros and Const for Fiber laxative
Pros
•Powder can come in orange flavor with some sugar-free options
•Also available as capsules, for people who don't like the powder or find it inconvenient
•Available OTC so you don't need a prescription
Cons
•Must take with a lot of liquid so you don't choke on the medication
•Can take 12 to 72 hours to relieve constipation
•Can cause bloating, especially when you first start
Common Side Effects of Senexon-s vs. Metamucil
Common Side Effects for
See Risks and Warnings
Common Side Effects for
•Change in bowel habits
•Bloating
Warnings of Senexon-s vs. Metamucil
Common Side Effects for
•Complete or partial blockage of intestines
•Self-medication
Common Side Effects for
•Choking
•Can contain phenylalanine
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