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Compare Movantik vs. Senexon-s

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Movantik (naloxegol) and Senna-S (docusate/senna) are both used to treat constipation, but they work in different ways and are used for different types of constipation. Movantik is an opioid antagonist specifically designed to treat constipation caused by opioid medications in adults. It blocks opioid receptors in the intestines, helping to move waste through the gut more easily. You take it once daily on an empty stomach, and it requires a prescription. Common side effects include stomach pain, diarrhea, and nausea. On the other hand, Senna-S is a combination of a stool softener and a stimulant laxative, used for occasional constipation. Docusate draws water into the intestines to soften the stool, while senna stimulates the intestines to push the stool out. It is available over-the-counter and can be taken daily, usually at bedtime, to produce a bowel movement by morning. Common side effects include stomach cramps and loose stools. Unlike Movantik, Senna-S should only be used short-term, typically less than 7 days.

  • Movantik (naloxegol)
    Docusate/senna
  • Movantik (naloxegol)
    Docusate/senna

  • Summary of Movantik vs. Senexon-s

    Summary for Opioid antagonist
    Prescription only

    Movantik (naloxegol) is an opioid antagonist that's used to treat opioid-induced constipation, or constipation from opioid medications, in adults. It's a tablet that's taken by mouth once every morning on an empty stomach. The dosage is typically 25 mg, but it can be lowered to lessen side effects or risks from interactions with other medications. Common side effects include stomach pain, diarrhea, and nausea. Movantik (naloxegol) is available as a brand-name medication only; there's no lower-cost generic version yet.

    Summary for Stool softener / Stimulant laxative

    Docusate/senna is a combination medication containing docusate and senna. The two laxatives work together to treat constipation.

  • Indications of Movantik vs. Senexon-s

    Indications for
    •Constipation from opioid pain medications in adults
    Indications for
    •Occasional constipation

  • Pros and Cons of Movantik vs. Senexon-s

    Pros and Const for Opioid antagonist
    Pros
    •A good option to help with constipation from opioids
    •Taken by mouth once a day
    •Tablets can be crushed and mixed with water for people who have trouble swallowing them whole
    Cons
    •Must take on an empty stomach
    •Might have opioid withdrawal symptoms
    •Might not work as well if you've been taking opioids for less than 1 month
    Pros and Const for Stool softener / Stimulant laxative
    Pros
    •Contains two medications, so there's fewer pills and can sometimes be cheaper
    •Available over-the-counter so you don't need a prescription from your provider
    •Works fast to help you have a bowel movement
    Cons
    •Should only be used short-term (less than 7 days)
    •Some people have stomach cramps
    •Can cause loose, watery stools

  • Common Side Effects of Movantik vs. Senexon-s

    Common Side Effects for
    •Stomach pain (up to 21%)
    •Diarrhea (up to 9%)
    •Nausea (up to 8%)
    Common Side Effects for

    See Risks and Warnings

  • Warnings of Movantik vs. Senexon-s

    Common Side Effects for
    •Opioid withdrawal
    •Severe stomach pain or diarrhea
    •Gastrointestinal (stomach or intestinal) injury
    •Allergic reaction
    Common Side Effects for
    •Complete or partial blockage of intestines
    •Self-medication

  • Prices with our coupons for Movantik vs. Senexon-s

    Learn more about Movantik
    Learn more about Docusate/senna

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