Key takeaways
Movantik (naloxegol) and MiraLAX (polyethylene glycol 3350) are both used to treat constipation, but they work in different ways and are used for different types of constipation. Movantik is an opioid antagonist that specifically treats constipation caused by opioid medications. It blocks opioid receptors in the intestines, helping you have a bowel movement. Movantik is a prescription-only medication and does not have a generic version. On the other hand, MiraLAX is an over-the-counter osmotic laxative that treats occasional constipation by drawing water into the colon to soften the stool. MiraLAX is available in generic forms like GaviLAX and Clearlax. Movantik is taken as a tablet on an empty stomach, while MiraLAX is a powder mixed with a beverage. Movantik can cause side effects like stomach pain and diarrhea, whereas MiraLAX may cause nausea, bloating, and gas.
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