Key takeaways
Suprep (sodium sulfate/potassium sulfate/magnesium sulfate) and Miralax (polyethylene glycol 3350) are both osmotic laxatives, but they are used for different purposes. Suprep is a prescription medication used to clean out your colon before a colonoscopy, while Miralax is an over-the-counter medication for occasional constipation. Suprep requires a two-dose regimen taken the night before and the morning of your procedure, whereas Miralax is typically taken once a day for up to a week. Miralax usually takes 1 to 3 days to work. Suprep can cause side effects like stomach discomfort and bloating, and it may not be suitable for people with kidney problems. On the other hand, Miralax is generally well-tolerated but can cause nausea, bloating, and gas. Suprep is not available over-the-counter, unlike Miralax, which you can buy without a prescription.
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