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Amitiza (lubiprostone) is a laxative used to treat chronic constipation and constipation caused by opioids. Amitiza is the only drug in the chloride channel activators class. There are currently no generic alternatives to Amitiza.
Check our savings tips for co-pay cards, assistance programs, and other ways to reduce your cost. Amitiza is covered by most Medicare and insurance plans.
Get Lubiprostone for as low as $33.44, which is 90% off the average retail price of $328.39 for the most common version, by using a GoodRx coupon.
| Dosage | Quantity | Retail price | GoodRx price |
|---|
| 8mcg | 60 capsules | $309.40 | $41.39 |
| 24mcg | 60 capsules | $309.46 | $43.44 |
Popular offers
Get an extra $10.00 off Lubiprostone and up to 90% off all prescriptions. Gold plans start at just $9.99/mo. Cancel any time.*
GoodRx coupon prices last updated on 04/12/26.
*Prices subject to change without notice. Sales tax may apply and is not included.
