The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Nausea (29%)
- Diarrhea (12%)
- Headache (11%)
- Stomach pain (8%)
- Stomach bloating (6%)
- Feeling gassy (6%)
Less Common Side Effects
- Vomiting
- Indigestion
- Loose stools
- Swelling from fluid buildup
- Dizziness
- Chest discomfort or pain
- Trouble breathing
- Tiredness
- Dry mouth
Note: Side effects were from adults with chronic constipation. Side effects might be different for other types of constipation.
Amitiza serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Severe diarrhea
- Low blood pressure or fainting: dizziness, lightheadedness
- Trouble breathing: chest tightness, trouble taking in a breath
Source: DailyMed
The following Amitiza side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
full or bloated feeling or pressure in the stomach
stomach pain
swelling of the abdominal or stomach area
Less common
Black, tarry stools
blood in the stools
chest discomfort or pain
chills
colds
difficult or labored breathing
general feeling of discomfort or illness
headache
increased sweating
joint pain
loss of appetite
loss of bowel control
muscle aches and pains
shivering
stomach discomfort
sweating
tightness in the chest
trouble sleeping
unusual tiredness or weakness
vomiting
Incidence not known
Blurred vision
confusion
difficulty with swallowing
dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
fainting
fast, pounding, or irregular heartbeat or pulse
hives or skin rash
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
stomach tenderness
swelling
Get emergency help immediately if any of the following symptoms of overdose occur:
Symptoms of overdose
Dry heaves
feeling of warmth
lack or loss of strength
paleness of the skin
redness of the face, neck, arms, and occasionally, upper chest
severe, unusual tiredness or weakness
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common
Belching
bladder pain
bloody or cloudy urine
change in taste
cold sweats
difficult, burning, or painful urination
difficulty with moving
discouragement
dizziness
fear or nervousness
feeling sad or empty
frequent urge to urinate
increased weight
indigestion
irritability
loss of interest or pleasure
loss of taste
lower back or side pain
muscle cramps
muscle stiffness
stomach upset
swollen joints
tingling of the hands or feet
unusual drowsiness, dullness, tiredness, or feeling of sluggishness
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Other Amitiza articles
Why trust our experts?







