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Fluticasone Propionate HFA Coupon - Fluticasone Propionate HFA 110mcg hfa inhaler

fluticasone

Generic Flovent
Used for Asthma

Fluticasone propionate inhaler, the generic name for Flovent, is an inhaled corticosteroid medication used everyday to help control asthma in adults and children ages 4 years and older. It comes as HFA and Diskus inhalers that are typically used twice a day. It's not a rescue inhaler and won't treat an asthma attack that's already started. Common side effects include throat irritation and upper respiratory tract infections.

Reviewed by:Last reviewed on October 7, 2026
basics-icon

What is Fluticasone?

Featuring Alyssa Billingsley, PharmDReviewed by Stacia Woodcock, PharmD | March 28, 2025

What is Fluticasone used for?

  • Maintenance treatment of asthma in adults and children ages 4 years and older

How Fluticasone works

Fluticasone is an inhaled corticosteroid. It works directly in your lungs to lower inflammation and swelling in your airways. This helps keep your airways open, control asthma symptoms, and prevent asthma attacks.

When does Fluticasone start working?Time passed since treatment started:
HOURS
DAYS
Initial effect
WEEKS
Full effect
MONTHS

Drug facts

Common BrandsFlovent(brand no longer available)
Drug ClassInhaled corticosteroid (ICS)
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only
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Side effects of Fluticasone

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

HFA (adults and children 12 years and older):

  • Upper respiratory tract infection (up to 18%)
  • Headache (up to 11%)
  • Throat irritation (up to 10%)
  • Sinus infection (up to 7%)
  • Hoarseness (up to 6%)
  • Bronchitis (up to 6%)
  • Cough (up to 6%)
  • Oral thrush (up to 5%)

Diskus:

  • Throat irritation (up to 22%)
  • Upper respiratory tract infection (up to 21%)
  • Headache (up to 14%)
  • Sinus infection (up to 10%)
  • Oral thrush (up to 9%)
  • Bronchitis (up to 8%)
  • Nausea and vomiting (up to 8%)
  • Fever (up to 7%)
  • Cough (up to 5%)
  • Muscle pain (up to 5%)

Less Common Side Effects

HFA (adults and children 12 years and older):

  • Runny or stuffy nose
  • Diarrhea
  • Indigestion
  • Stomach discomfort and pain
  • Muscle pain
  • Dizziness
  • Migraines
  • Fever

Diskus:

  • Runny or stuffy nose
  • Stomach discomfort and pain
  • Hoarseness
  • Bruising
  • Nosebleed
  • Teeth pain
  • Weight gain
  • Changes in appetite
  • Dizziness
  • Sleep problems
  • Acne

Fluticasone serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Sudden narrowing of the airways: worsening trouble breathing, coughing, wheezing
  • Severe allergic reaction: rash, hives, swelling of the face or tongue, breathing problems
  • Other infections: fever, body aches, tiredness, vomiting, pain, chills, nausea
When do Fluticasone possible side effects begin and end?
Time passed since treatment started:
M
H
D
W
M
Throat irritation
Cough
Voice hoarseness
Risk of thrush
Risk of respiratory infections
If a line continues to the right, you'll likely keep experiencing this side effect once it starts.

Source: DailyMed

The following Fluticasone side effects have also been reported

Side effects that you should report to your care team as soon as possible:

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

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Pros and cons of Fluticasone

Pros

  • Helps prevent and control asthma symptoms
  • Approved for adults and children ages 4 years and older
  • Available as two types of inhalers: HFA and Diskus
  • Available in several strengths to help adjust treatment

Cons

  • Requires daily use, typically twice a day
  • Doesn't treat sudden asthma attacks
  • Can cause thrush (fungal infection) in the mouth or throat
  • Long-term use can slow growth in children
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Pharmacist tips for Fluticasone

pharmacist
  • Use fluticasone twice a day, about 12 hours apart, around the same times each day. Use it every day for the best results.
  • Rinse your mouth with water and spit it out after each dose of fluticasone. This helps prevent a fungal infection in your mouth or throat called thrush.
  • Fluticasone won't treat sudden breathing problems or an asthma attack. Use your rescue inhaler, such as albuterol, as directed for sudden symptoms.
  • Contact your care team if your breathing or peak flow meter results get worse while using fluticasone, or if your rescue inhaler isn't working as well. Also let them know if you need your rescue inhaler more often than usual, since your asthma treatment might need to be adjusted.
  • Pregnancy: Talk to your prescriber about using fluticasone if you're pregnant or planning to become pregnant. There isn't much information about its use during pregnancy, but poorly controlled asthma can cause problems for you and your unborn baby. Current asthma guidelines recommend continuing inhaled corticosteroid treatment during pregnancy.
  • Breastfeeding: It isn't known whether fluticasone passes into breast milk or affects a breastfed baby. Talk to your prescriber about the risks and benefits of using it while breastfeeding.
  • Storage: Keep fluticasone at room temperature away from heat and direct light. Store the HFA inhaler with the mouthpiece facing down.

How to use fluticasone propionate HFA inhaler:

  • Prime the inhaler: Prime your HFA inhaler before using it for the first time, if you haven't used it for more than 7 days, or if you drop it. Shake it for 5 seconds and spray it into the air away from your face. For a new inhaler, repeat this 3 more times.
  • Taking a dose: Shake the HFA inhaler and breathe out fully. Put the mouthpiece in your mouth, start breathing in slowly and deeply, and press the canister once as you continue breathing in. Hold your breath for about 10 seconds or as long as comfortable, and repeat if you need a second puff.
  • Cleaning: Clean the HFA inhaler mouthpiece at least once a week after your evening dose. Use cotton swabs and tissues dampened with water, then let it air-dry overnight.

How to use fluticasone propionate Diskus inhaler:

  • Write use-by date: When you remove the Diskus inhaler from its foil pouch, write down the date you opened it and its use-by date. Throw away the 50 mcg strength after 6 weeks and the 100 mcg and 250 mcg strengths after 2 months.
  • Taking a dose: Breathe out fully away from the Diskus inhaler, then place the mouthpiece between your lips and breathe in quickly and deeply through your mouth. Remove the inhaler, hold your breath for about 10 seconds or as long as comfortable, then breathe out slowly.
  • Cleaning: Wipe with a dry cloth as needed. Don't wash the inhaler or get it wet because moisture can cause the powder to clump and clog the device.
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Risks and warnings for Fluticasone

Fluticasone can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

Fungal infection in the mouth or throat

  • Risk factor: Not rinsing and spitting after using fluticasone

Fluticasone can cause a fungal infection called thrush in your mouth or throat. To lower your risk, rinse your mouth with water and spit it out after every dose.

Tell your care team if you develop white patches, redness, or soreness in your mouth or throat. You might need an antifungal medication, and sometimes you might need to pause fluticasone until the infection improves.

Worsening asthma

  • Risk factors: Using albuterol more often

Fluticasone is a maintenance inhaler that works over time to control asthma. It doesn't open your airways quickly and shouldn't be used as a rescue inhaler during an asthma attack.

Use your rescue inhaler, such as albuterol, as directed for sudden breathing problems. Contact your care team right away if your rescue inhaler isn't helping, since you might need additional treatment.

Higher risk of infections

  • Risk factors: Active, chronic (long-term), or recurrent infection | Medical conditions that weaken the immune system | Taking other medications that can weaken the immune system

Fluticasone can weaken your immune system and make it harder for your body to fight infections. Certain infections, such as chickenpox and measles, can become more serious. Avoid close contact with people who have these infections, and contact your care team right away if you're exposed.

Tell your care team about any current or past infections before starting fluticasone, including tuberculosis (TB), fungal, bacterial, viral, or parasitic infections, or herpes infections of the eye. Contact them if you develop signs of an infection, such as fever, chills, or body aches.

Changes in stress hormone levels

  • Risk factors: High doses of fluticasone | Using fluticasone long term | Stressful events (e.g., surgery)

Fluticasone can rarely affect your body's ability to make its own steroid hormones. At recommended doses, this is less likely to happen. But using high doses or more than prescribed can lead to adrenal insufficiency, a condition where your body doesn't make enough steroid hormones.

Tell your care team if you develop unusual tiredness, weakness, dizziness, nausea, or vomiting, especially during illness, surgery, or other physical stress.

Serious allergic reactions

  • Risk factors: Allergy to milk proteins (lactose) - Diskus only

Both the HFA and Diskus forms of fluticasone can rarely cause a serious or life-threatening allergic reaction, including anaphylaxis. Get emergency medical help right away if you develop hives, a rash, swelling of your face or throat, trouble breathing, or severe dizziness.

The Diskus inhaler contains lactose, which can contain small amounts of milk proteins. Don't use the Diskus form if you have a severe milk protein allergy.

Risk of bone loss

  • Risk factors: Using fluticasone long term | Older adult | Unable to move for a long period of time | Family history of osteoporosis | Poor diet | Postmenopausal | Smoking | Using medications that can cause bone loss

Long-term use of fluticasone might lower your bone mineral density, which can weaken your bones. It's not clear how much this affects your risk of broken bones. Your care team might check your bone health if you're at higher risk.

Slowed growth in children

Fluticasone might slow growth in children who are still growing. Your child's care team will likely check their height regularly during treatment and use the lowest dose that keeps their asthma under control.

Eye problems

  • Risk factors: Long-term use of fluticasone

Long-term use of fluticasone can raise your risk of eye problems, including glaucoma, glaucoma and cataracts. Tell your care team if you notice blurry vision, eye pain, or other changes in your eyesight. If you use fluticasone for a long time, your care team might recommend regular eye exams.

Sudden narrowing of the airways

Fluticasone can sometimes cause paradoxical bronchospasm, which means your airways tighten instead of relax. This is rare but can be life threatening. If you notice more wheezing, shortness of breath, or coughing after using fluticasone, stop using it and use a rescue inhaler (like albuterol) right away. Contact your prescriber since you might need to switch to a different treatment.

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Fluticasone dosage

The average cost for 1 hfa inhaler of 110mcg of Fluticasone is $170.28 with a free GoodRx coupon. This is 42.67% off the average retail price of $297.00.
hfa inhalerHfa inhaler
DosageQuantityPrice as low asPrice per unit
44mcg1 hfa inhaler$117.98$117.98
110mcg1 hfa inhaler$170.28$170.28
220mcg1 hfa inhaler$248.80$248.80
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How much does Fluticasone cost?

To access savings, use a GoodRx coupon and pay just a fraction of the retail price.
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Fluticasone contraindications

Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Fluticasone will not be safe for you to take.

  • Treatment of sudden asthma attack
  • Severe milk protein allergy (for Diskus only)
alternatives-icon

What are alternatives to Fluticasone?

There are a number of medications that your doctor can prescribe in place of Fluticasone. Compare a few possible alternatives below.
Fluticasone
Used for:
  • Maintenance treatment of asthma in adults and children ages 4 years and older
$117.98Lowest GoodRx priceView prices
Used for:
  • Maintenance treatment of asthma in people ages 5 years and older
$105.00Lowest GoodRx priceView prices
Used for:
  • Maintenance treatment of asthma in people ages 4 years and older
$196.74Lowest GoodRx priceView prices
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News about Fluticasone

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Fluticasone images

Not applicable - Fluticasone Propionate HFA 110mcg/actuation Inhalation Aerosol
This medicine is Colorless Hfa Inhaler.Not applicable - Fluticasone Propionate HFA 110mcg/actuation Inhalation Aerosol

References

Best studies we found

American Lung Association. (2026). Measuring your peak flow rate.

Galván, C. A. (2012). Practical considerations for dysphonia caused by inhaled corticosteroids. Mayo Clinic Proceedings.

Global Initiative for Asthma. (2026). Summary guide for asthma management and prevention.

Jette-Kelly, L. A. (2018). Paradoxical bronchoconstriction with short-acting beta agonist. American Journal of Case Reports.

Prasco Laboratories. (2023). Fluticasone propionate DISKUS (fluticasone propionate inhalation powder) [package insert]. DailyMed.

Prasco Laboratories. (2023). Fluticasone propionate HFA inhalation aerosol [package insert]. DailyMed.

Szefler, S. J., et al. (1999). Time to onset of effect of fluticasone propionate in patients with asthma. The Journal of Allergy and Clinical Immunology.

GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.