Flovent vs. Arnuity Ellipta: 5 Differences Between These Asthma Inhalers

If you’re living with asthma, choosing the right inhaler can feel overwhelming. Flovent (fluticasone propionate) and Arnuity Ellipta (fluticasone furoate) are two options that may seem similar at first glance. But they have some important differences to consider — from their inhaler types to how long they work.

So, how else do Flovent and Arnuity Ellipta compare? We cover five key differences you should know below.

Note: In early 2024, brand-name Flovent was discontinued. This is because authorized generics of Flovent HFA and Flovent Diskus are now available. For simplicity, we’ll refer to the authorized generics as Flovent in this article.

1. Flovent and Arnuity Ellipta contain different forms of fluticasone

Both Flovent and Arnuity Ellipta use fluticasone as their active ingredient, a corticosteroid that reduces inflammation in the airways of the lungs. But they contain slightly different versions of it. Flovent contains fluticasone propionate and Arnuity Ellipta contains fluticasone furoate.

Both forms work similarly to reduce lung inflammation, but they differ in potency and duration of action. Fluticasone furoate is more potent and lasts longer in the lungs and body than fluticasone propionate.

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2. Flovent is used twice daily, while Arnuity Ellipta is used once daily

One of the biggest differences between Flovent and Arnuity Ellipta is the dose frequency. Flovent is typically prescribed to be used twice daily — once in the morning and once in the evening. Arnuity Ellipta is more potent with longer-lasting effects. Because of this, it’s used only once daily, usually at the same time each day.

If you prefer a simpler regimen or have difficulty remembering to take medications multiple times a day, Arnuity Ellipta can be a more convenient option.

3. Flovent and Arnuity Ellipta come in different types of inhalers

Another difference between Flovent and Arnuity Ellipta is the type of inhaler device they come in. Flovent is available as both a metered-dose inhaler (Flovent HFA) and a dry powder inhaler (Flovent Diskus). Arnuity Ellipta comes only as a dry powder inhaler.

Metered-dose inhalers (MDIs) deliver the medication as a pressurized spray that you inhale into your lungs. Dry powder inhalers (DPIs) release a fine powder when you inhale through the device. Each inhaler type has its own technique. MDIs require coordination between pressing the canister and inhaling. DPIs rely on your ability to take a deep, forceful breath.

For some people, the inhaler type and inhalation technique may play a role in choosing one option over the other.

4. Flovent and Arnuity Ellipta are approved for slightly different ages

Flovent and Arnuity Ellipta are both approved for asthma, but the age groups they’re approved for vary slightly.

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Both inhalers are approved for adults. But Flovent is approved for children as young as 4 years old, and Arnuity Ellipta is approved for children age 5 and older. Although the age difference is small, it can be a factor that’s considered for young children.

5. Flovent has authorized generics, while Arnuity Ellipta is brand-name only

Cost is often an important consideration when it comes to asthma inhalers. And with Flovent and Arnuity Ellipta, there’s a difference between their options for affordability.

As mentioned earlier, brand-name Flovent has been discontinued. Authorized generics for Flovent HFA and Flovent Diskus are now available in its place. These products are the same as Flovent, but without the brand name. They’re also sold at a lower price. But what you end up paying can depend on your insurance coverage.

Arnuity Ellipta is currently only available as a brand-name product. This can make it more expensive, depending on your insurance coverage.

Which inhaler is right for you?

Choosing between Flovent and Arnuity Ellipta may depend on several factors, including age, dose frequency, and inhaler type.

If you prefer an MDI and a twice-daily dose is manageable, Flovent could be a good option. But if you prefer a once-daily medication, Arnuity Ellipta may be more convenient. Your healthcare team can help you determine which inhaler best fits your needs. It’s also a good idea to contact your insurance plan to check your coverage and out-of-pocket costs.

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Written by Mandy Armitage, MD

How to save on Flovent and Arnuity Ellipta

There are ways that you can save money on Flovent authorized generics and Arnuity Ellipta. With a free GoodRx coupon, the price of generic Flovent HFA is as low as $168.90 and the price of generic Flovent Diskus is as low as $134.09.

For Arnuity Ellipta, you may be eligible to pay as little as $35 for your inhaler. Other ways to save include patient assistance programs and GoodRx coupons. At certain pharmacies the price is as low as $208.79 with GoodRx.

Why trust our experts?

Written by:

Alyssa Billingsley, PharmD

Alyssa Billingsley, PharmD, is the director of pharmacy content for GoodRx. She has over a decade of experience as a pharmacist and has worked in clinical, academic, and administrative roles.

Reviewed by:

Kristine Foley, PharmD

Kristine Foley is a licensed pharmacist with over 13 years of community pharmacy experience. She earned her Doctor of Pharmacy degree from Rutgers University.

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