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Zyrtec vs. Allegra-D

Cetirizine (Zyrtec) is an antihistamine. It's used for relief of allergy symptoms, such as runny nose or watery eyes, in adults and children. Cetirizine (Zyrtec) is also a safe option for people who are pregnant. This medication is available in different formulations, including tablets and liquid solutions. Typically, cetirizine (Zyrtec) is taken by mouth once per day. The most common side effect of cetirizine (Zyrtec) is sleepiness. But it's less likely to make you drowsy compared to some other antihistamines, such as diphenhydramine (Benadryl).

• Short-term relief of allergy symptoms (sneezing, runny nose, itchy or watery eyes, itching of the nose or throat)
• Relief of itchiness due to chronic (long-term) hives in children ages 6 months to under 6 years old - certain liquid solutions only

People 12 years of age and older:

• Sleepiness (14%)
• Tiredness (6%)
• Dry mouth (5%)

Children age 6 to under 12 years:

• Headache (11-14%)
• Sore throat (3-6%)
• Stomach pain (4-6%)
• Cough (3-4%)
• Sleepiness (2-4%)

• Sleepiness
• Accidentally taking too much medication

Allegra-D is a combination of two medications: pseudoephedrine (a decongestant) and fexofenadine (an antihistamine). It's taken by people ages 12 years and older to relieve allergy symptoms, like sinus congestion and runny nose. Allegra-D (fexofenadine / pseudoephedrine) is taken by mouth, either every 12 hours or every 24 hours, depending on the formulation (Allegra-D 12-hour or Allegra-D 24-hour. Some common side effects include headache and trouble sleeping. This medication is available as both brand name and generics.

Short-term relief of allergy symptoms in adults and children ages 12 years and older:

• Itchy nose or throat
• Sneezing
• Itchy or watery eyes
• Runny or stuffy nose
• Sinus congestion or pressure

• Trouble sleeping (11%)
• Headache (9%)
• Nausea (6%)

• Fast heart rate and high blood pressure
• Worsening of certain medical conditions
• Accidentally taking too much medication