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Compare Yupelri vs. Albuterol

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Revefenacin (Yupelri) and albuterol are both prescription medications used to help with breathing problems, but they work differently and are used for different purposes. Both are used to treat chronic obstructive pulmonary disease (COPD), but albuterol is also used for asthma, including exercise-induced asthma. Revefenacin is a long-acting muscarinic antagonist (LAMA) taken once daily using a nebulizer, while albuterol is a short-acting beta agonist (SABA) used as needed with either an inhaler or a nebulizer. Revefenacin is only available as a brand-name medication, whereas albuterol is available in both branded and generic forms. Common side effects of revefenacin include cough and headache, while albuterol can cause sore throat and throat irritation. Albuterol works quickly to relieve sudden breathing problems, but it may need to be used multiple times a day. Revefenacin is a maintenance medication and should not be used for sudden symptoms.

  • Yupelri (revefenacin)
    Albuterol
  • Yupelri (revefenacin)
    Albuterol

  • Summary of Yupelri vs. Albuterol

    Summary for LAMA
    Prescription only

    Yupelri (revefenacin) is an inhalation solution that's used to treat adults with chronic obstructive pulmonary disease (COPD). It belongs to the drug class called long-acting muscarinic antagonists, or LAMAs. Yupelri (revefenacin) is inhaled through the mouth once a day using a nebulizer machine. Some possible side effects include headache and cough. Yupelri (revefenacin) is a brand-name medication; there's currently no generic version available.

    Summary for SABA
    Prescription only

    Albuterol sulfate is a short-acting beta agonist (SABA). It's a rescue inhaler that treats or prevents sudden wheezing or shortness of breath in adults and children at least 4 years old with certain breathing problems, such as asthma. Albuterol is inhaled through the mouth using either an HFA inhaler (or metered dose inhaler) or a dry powder inhaler. The typical dose is 2 inhalations every 4 to 6 hours as needed when you suddenly have trouble breathing. Albuterol side effects generally include sore throat, throat irritation, and infections.

  • Indications of Yupelri vs. Albuterol

    Indications for
    •Chronic obstructive pulmonary disease (COPD)
    Indications for
    •Treatment or prevention of wheezing or tightening of airways in people ages 4 years and older with certain types of lung problems (e.g., asthma)
    •Prevention of exercise-induced asthma in people ages 4 years and older

  • Pros and Cons of Yupelri vs. Albuterol

    Pros and Const for LAMA
    Pros
    •Only taken once a day
    •Works quickly (within 5 minutes) and lasts the whole day
    •Easy to breathe in; there isn't as much timing and technique needed like for COPD inhalers
    Cons
    •Must set up the nebulizer machine before each dose
    •Takes about 8 minutes to take a full dose
    •Not a good option for people with liver damage because of higher risk of side effects
    Pros and Const for SABA
    Pros
    •Works within minutes to help you breathe easier when you have an asthma attack or trouble breathing
    •Only used as needed when you're short of breath or when you're about to exercise
    •Can be used by children as young as 4 years old
    •Available as two types of inhalers: HFA inhaler (or metered dose inhaler) and dry powder inhaler
    Cons
    •Might have to use the inhaler multiple times per day since it's a short-acting medication
    •Might be difficult for some people to use the inhaler properly
    •Should carry with you at all times so you can use it when you need to

  • Common Side Effects of Yupelri vs. Albuterol

    Common Side Effects for
    •Cough (4%)
    •Symptoms of a common cold (4%)
    •Upper respiratory tract infection (4%)
    •Headache (4%)
    •Back pain (2%)
    Common Side Effects for
    •Sore throat
    •Throat irritation
    •Runny nose
    •Upper respiratory infection

    Note: Side effects you might have can depend on your age, dose, the type of albuterol inhaler you're using, and how often you're using the inhaler.

  • Warnings of Yupelri vs. Albuterol

    Common Side Effects for
    •Sudden trouble breathing
    •Eye problems
    •Problems with urination
    •Allergic reactions
    Common Side Effects for
    •Breathing problems
    •Heart problems
    •Low potassium in the blood
    •Allergic reactions

  • Prices with our coupons for Yupelri vs. Albuterol

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    Learn more about Albuterol

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