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Yupelri vs. Albuterol

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Revefenacin (Yupelri) and albuterol are both prescription medications used to help with breathing problems, but they work differently and are used for different purposes. Both are used to treat chronic obstructive pulmonary disease (COPD), but albuterol is also used for asthma, including exercise-induced asthma. Revefenacin is a long-acting muscarinic antagonist (LAMA) taken once daily using a nebulizer, while albuterol is a short-acting beta agonist (SABA) used as needed with either an inhaler or a nebulizer. Revefenacin is only available as a brand-name medication, whereas albuterol is available in both branded and generic forms. Common side effects of revefenacin include cough and headache, while albuterol can cause sore throat and throat irritation. Albuterol works quickly to relieve sudden breathing problems, but it may need to be used multiple times a day. Revefenacin is a maintenance medication and should not be used for sudden symptoms.

Yupelri

(revefenacin)

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Albuterol

 

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Summary for Yupelri

Prescription only

Yupelri (revefenacin) is an inhalation solution that's used to treat adults with chronic obstructive pulmonary disease (COPD). It belongs to the drug class called long-acting muscarinic antagonists, or LAMAs. Yupelri (revefenacin) is inhaled through the mouth once a day using a nebulizer machine. Some possible side effects include headache and cough. Yupelri (revefenacin) is a brand-name medication; there's currently no generic version available.

Indications for Yupelri

Pros and Cons for Yupelri

Pros

  • Only taken once a day
  • Works quickly (within 5 minutes) and lasts the whole day
  • Easy to breathe in; there isn't as much timing and technique needed like for COPD inhalers

Cons

  • Must set up the nebulizer machine before each dose
  • Takes about 8 minutes to take a full dose
  • Not a good option for people with liver damage because of higher risk of side effects

Common Side Effects for Yupelri

Warnings for Yupelri

  • Sudden trouble breathing
  • Eye problems
  • Problems with urination
  • Allergic reactions

Summary for Albuterol

Prescription only

Albuterol sulfate is a short-acting beta agonist (SABA). It's a rescue inhaler that treats or prevents sudden wheezing or shortness of breath in adults and children at least 4 years old with certain breathing problems, such as asthma. Albuterol is inhaled through the mouth using either an HFA inhaler (or metered dose inhaler) or a dry powder inhaler. The typical dose is 2 inhalations every 4 to 6 hours as needed when you suddenly have trouble breathing. Albuterol side effects generally include sore throat, throat irritation, and infections.

Indications for Albuterol

  • Treatment or prevention of wheezing or tightening of airways in people ages 4 years and older with certain types of lung problems (e.g., asthma)
  • Prevention of exercise-induced asthma in people ages 4 years and older

Pros and Cons for Albuterol

Pros

  • Works within minutes to help you breathe easier when you have an asthma attack or trouble breathing
  • Only used as needed when you're short of breath or when you're about to exercise
  • Can be used by children as young as 4 years old
  • Available as two types of inhalers: HFA inhaler (or metered dose inhaler) and dry powder inhaler

Cons

  • Might have to use the inhaler multiple times per day since it's a short-acting medication
  • Might be difficult for some people to use the inhaler properly
  • Should carry with you at all times so you can use it when you need to

Common Side Effects for Albuterol

Note: Side effects you might have can depend on your age, dose, the type of albuterol inhaler you're using, and how often you're using the inhaler.

Warnings for Albuterol

  • Breathing problems
  • Heart problems
  • Low potassium in the blood
  • Allergic reactions

Prices with our coupons for Yupelri vs. Albuterol

Price Card Drug Icon
Yupelri1 carton / 30 vials of 175mcg/3ml
$1,579.98$2,022.38
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Albuterol1 hfa inhaler / 18g of 90mcg
$32.10$46.43
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