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Tiotropium vs. Albuterol

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Spiriva

(tiotropium)

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Albuterol

 

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Summary for Tiotropium

Prescription only

Spiriva (tiotropium) is a medication used to help control chronic obstructive pulmonary disease (COPD) and asthma. There are two different Spiriva inhalers: Spiriva Respimat is a metered-dose inhaler, and Spiriva HandiHaler is a device that you place a capsule of medication into before you take the medication. The typical dosage for Spiriva (tiotropium) is two inhalations once a day, but the dose depends on the reason you're using it. Side effects include dry mouth, cough, and upper respiratory tract infections. Only Spiriva HandiHaler is also available as a generic version.

Indications for Tiotropium

  • Chronic obstructive pulmonary disease (COPD)
  • Asthma in people age 6 years and older - Spiriva Respimat only

Pros and Cons for Tiotropium

Pros

  • Helps prevent attacks or flare-ups
  • Has few side effects
  • Used once daily
  • Doesn't commonly cause a fast heart rate like some other bronchodilators
  • Available as a lower-cost generic (Spiriva HandiHaler only)

Cons

  • Doesn't work fast enough to be used as a rescue inhaler for attacks
  • Can be difficult for some people to use
  • Can cause dry mouth as a side effect
  • Only Spiriva Respimat can be used for asthma in children 6 years and older
  • Spiriva Respimat is currently only available as brand name

Common Side Effects for Tiotropium

Spiriva HandiHaler and generic

Spiriva Respimat

  • Sore throat (12%)
  • Cough (6%)
  • Dry mouth (4%)
  • Sinus inflammation (3%)

Warnings for Tiotropium

  • Not a rescue inhaler
  • Allergic reaction
  • Sudden airway tightening (paradoxical bronchospasm)
  • Worsening glaucoma
  • Urination problems
  • Higher risk for side effects in people with kidney problems

Summary for Albuterol

Prescription only

Albuterol sulfate is a short-acting beta agonist (SABA). It's a rescue inhaler that treats or prevents sudden wheezing or shortness of breath in adults and children at least 4 years old with certain breathing problems, such as asthma. Albuterol is inhaled through the mouth using either an HFA inhaler (or metered dose inhaler) or a dry powder inhaler. The typical dose is 2 inhalations every 4 to 6 hours as needed when you suddenly have trouble breathing. Albuterol side effects generally include sore throat, throat irritation, and infections.

Indications for Albuterol

  • Treatment or prevention of wheezing or tightening of airways in people ages 4 years and older with certain types of lung problems (e.g., asthma)
  • Prevention of exercise-induced asthma in people ages 4 years and older

Pros and Cons for Albuterol

Pros

  • Works within minutes to help you breathe easier when you have an asthma attack or trouble breathing
  • Only used as needed when you're short of breath or when you're about to exercise
  • Can be used by children as young as 4 years old
  • Available as two types of inhalers: HFA inhaler (or metered dose inhaler) and dry powder inhaler

Cons

  • Might have to use the inhaler multiple times per day since it's a short-acting medication
  • Might be difficult for some people to use the inhaler properly
  • Should carry with you at all times so you can use it when you need to

Common Side Effects for Albuterol

Note: Side effects you might have can depend on your age, dose, the type of albuterol inhaler you're using, and how often you're using the inhaler.

Warnings for Albuterol

  • Breathing problems
  • Heart problems
  • Low potassium in the blood
  • Allergic reactions

Prices with our coupons for Tiotropium vs. Albuterol

Price Card Drug Icon
Tiotropium1 inhaler / 30 capsules of 18mcg per capsule
$76.57$362.30
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Albuterol1 hfa inhaler / 18g of 90mcg
$32.10$42.93
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