Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Terbutaline (Brethine) and albuterol (Ventolin) are both medications used to treat breathing problems like asthma. They both work by relaxing the muscles in your lungs to help you breathe easier. However, they belong to different medication classes. Both medications are short-acting beta agonist (SABA) but terbutaline is available as an oral tablet and albuterol is available as an inhaler. Terbutaline is typically taken three times a day, whereas albuterol is used as needed, usually every 4 to 6 hours. Terbutaline is not recommended for children under 12, while albuterol can be used by children as young as 4 years old. Terbutaline is only available as a generic, while albuterol is available in both brand and generic forms. Common side effects of terbutaline include nervousness and a racing heart, while albuterol can cause sore throat and throat irritation.
Terbutaline
Albuterol
Terbutaline
Albuterol
Summary of Terbutaline vs. Albuterol
Summary for Beta-adrenergic agonist
Prescription only
Terbutaline is used to prevent and treat asthma attacks, but it isn’t a first-choice option to use when you're experiencing an asthma attack. Terbutaline is one of the few asthma medications that come as a tablet that's swallowed instead of an inhaler. Some side effects of terbutaline include nervousness, tremor (shakiness), and headache. It isn't safe to use during pregnancy because of the risk of harm to both mother and baby. This medication used to be sold under the brand name Brethine, but is now only available under the generic name.
Summary for SABA
Prescription only
Albuterol sulfate is a short-acting beta agonist (SABA). It's a rescue inhaler that treats or prevents sudden wheezing or shortness of breath in adults and children at least 4 years old with certain breathing problems, such as asthma. Albuterol is inhaled through the mouth using either an HFA inhaler (or metered dose inhaler) or a dry powder inhaler. The typical dose is 2 inhalations every 4 to 6 hours as needed when you suddenly have trouble breathing. Albuterol side effects generally include sore throat, throat irritation, and infections.
Indications of Terbutaline vs. Albuterol
Indications for
•Prevention and treatment of bronchospasm (narrowing of airways) related to asthma, bronchitis, and emphysema
Indications for
•Treatment or prevention of wheezing or tightening of airways in people ages 4 years and older with certain types of lung problems (e.g., asthma)