Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Vyvanse (lisdexamfetamine) and atomoxetine (Strattera) are both used to treat ADHD in adults and children age 6 years and older, but they have some key differences. Vyvanse is a stimulant and a controlled substance, meaning it has a high risk of misuse and dependency. Atomoxetine, on the other hand, is a non-stimulant and not a controlled substance, so it doesn't carry the same risk of addiction. However, it doesn’t improve ADHD symptoms as well as stimulant medications do. Vyvanse can also treat binge eating disorder in adults, while atomoxetine is only approved for ADHD. Vyvanse tends to work faster, often within a couple of hours, whereas atomoxetine may take a few weeks to show full effects. Additionally, Vyvanse is available in both capsule and chewable tablet forms, while atomoxetine is only available as capsules. Common side effects for Vyvanse include difficulty sleeping and loss of appetite, while atomoxetine can cause nausea and dry mouth. Both medications are available as low-cost generics.
Vyvanse (lisdexamfetamine)
Atomoxetine (Strattera)
Vyvanse (lisdexamfetamine)
Atomoxetine (Strattera)
Summary of Vyvanse vs. Strattera
Summary for Stimulant
Prescription only
Vyvanse, the brand name for lisdexamfetamine, is a stimulant medication. It's used to treat attention deficit-hyperactivity disorder (ADHD) in people 6 years and older. It can also treat binge eating disorder (BED) in adults. Vyvanse (lisdexamfetamine) comes as capsules and chewable tablets. It's taken once per day in the morning. The dosage starts low and gets adjusted based on how you respond to the medication. Common side effects include trouble sleeping and loss of appetite. Vyvanse (lisdexamfetamine) is a controlled substance because it has a high risk of misuse and dependency.
Summary for Selective norepinephrine reuptake inhibitor
Prescription only
Atomoxetine (Strattera) is a non-stimulant medication used to treat attention-deficit hyperactivity disorder (ADHD) in people 6 years of age and older. It's not a controlled substance like many other ADHD medications are. But atomoxetine (Strattera) still has potentially serious risks to consider, such as mental health problems and heart problems.