Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Vyvanse (lisdexamfetamine) and Adderall XR (dextroamphetamine / amphetamine salts) are both stimulant medications used to treat attention deficit-hyperactivity disorder (ADHD). They work by increasing levels of certain chemicals in the brain, such as norepinephrine, dopamine, and serotonin. However, Vyvanse is also FDA-approved for treating moderate-to-severe binge eating disorder (BED) in adults, while Adderall XR is not. Vyvanse is typically taken once per day in the morning, with a starting dose of 30 mg that can be gradually increased up to 70 mg. Adderall XR is also taken once daily, with starting doses varying by age and a maximum dosage of 30 mg for children and a recommended dosage of 20 mg per day for adults. Vyvanse is available in both capsule and chewable tablet forms, while Adderall XR is available as a capsule that can be opened and sprinkled on applesauce. Both medications have a risk of misuse and dependency and are controlled substances. Common side effects include difficulty sleeping, dry mouth, and loss of appetite. Both medications can interact with other drugs, especially those affecting serotonin levels, and may not be recommended if you have a history of heart problems.
Vyvanse (lisdexamfetamine)
Adderall xr
Vyvanse (lisdexamfetamine)
Adderall xr
Summary of Vyvanse vs. Adderall XR
Summary for Stimulant
Prescription only
Vyvanse, the brand name for lisdexamfetamine, is a stimulant medication. It's used to treat attention deficit-hyperactivity disorder (ADHD) in people 6 years and older. It can also treat binge eating disorder (BED) in adults. Vyvanse (lisdexamfetamine) comes as capsules and chewable tablets. It's taken once per day in the morning. The dosage starts low and gets adjusted based on how you respond to the medication. Common side effects include trouble sleeping and loss of appetite. Vyvanse (lisdexamfetamine) is a controlled substance because it has a high risk of misuse and dependency.
Summary for Stimulant
Prescription only
Adderall XR is the extended-release version of dextroamphetamine and amphetamine salt combo. It's a stimulant used to treat attention deficit-hyperactivity disorder (ADHD) in people 6 years and older. It comes as a capsule that you take once a day in the morning. The prescriber can adjust the dosage depending on how well it helps you focus and if you have side effects that bother you. These side effects can include low appetite, stomach pain, and trouble sleeping. It's a controlled substance because of its high risk of misuse and dependency. Adderall XR is available as a brand-name medication and a generic.