Key takeaways
Atomoxetine (Strattera) and dextroamphetamine (Dexedrine) are both used to treat attention-deficit hyperactivity disorder (ADHD), but they have some key differences. Atomoxetine is a selective norepinephrine reuptake inhibitor (NRI) and is not a controlled substance, meaning it has a lower risk of misuse and dependence. In contrast, dextroamphetamine is a stimulant and a Schedule II controlled substance, which means it has a higher risk of misuse and dependence. Atomoxetine can take a few weeks to show full effects, while dextroamphetamine can start working within 30 minutes to an hour. Dextroamphetamine is also used to treat narcolepsy, a condition characterized by extreme daytime sleepiness, whereas atomoxetine is not. Additionally, atomoxetine is available only as capsules, while dextroamphetamine comes in various forms, including tablets, extended-release capsules, and liquid solutions. Both medications have potential side effects, including heart-related side effects such as heart attack, and mental health-related issues like suicidal thoughts,
