Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Atomoxetine (Strattera) and dextroamphetamine (Dexedrine) are both used to treat attention-deficit hyperactivity disorder (ADHD), but they have some key differences. Atomoxetine is a selective norepinephrine reuptake inhibitor (NRI) and is not a controlled substance, meaning it has a lower risk of misuse and dependence. In contrast, dextroamphetamine is a stimulant and a Schedule II controlled substance, which means it has a higher risk of misuse and dependence. Atomoxetine can take a few weeks to show full effects, while dextroamphetamine can start working within 30 minutes to an hour. Dextroamphetamine is also used to treat narcolepsy, a condition characterized by extreme daytime sleepiness, whereas atomoxetine is not. Additionally, atomoxetine is available only as capsules, while dextroamphetamine comes in various forms, including tablets, extended-release capsules, and liquid solutions. Both medications have potential side effects, including heart-related side effects such as heart attack, and mental health-related issues like suicidal thoughts,
Atomoxetine (Strattera)
Dextroamphetamine
Atomoxetine (Strattera)
Dextroamphetamine
Summary of Strattera vs. Dexedrine
Summary for Selective norepinephrine reuptake inhibitor
Prescription only
Atomoxetine, also known by its brand name Strattera, is a non-stimulant medication. It's used to treat attention-deficit hyperactivity disorder (ADHD) in adults and children ages 6 years and up. Atomoxetine (Strattera) comes as capsules that are swallowed whole. You take your dosage either once or twice a day. Side effects are stomach upset and low appetite. It's not a controlled substance like some ADHD medications are. But atomoxetine (Strattera) still has a few serious risks like behavioral changes and heart problems.
Summary for Stimulant
Prescription only
Dextroamphetamine is used for the treatment of attention deficit-hyperactivity disorder (ADHD). It can also be used to treat uncontrollable daytime sleepiness (narcolepsy). Some side effects of the medication include difficulty sleeping, restlessness, and loss of appetite (that might lead to possible weight loss).