Key takeaways
Topiramate (Topamax, Qudexy XR, Trokendi XR, Eprontia) and propranolol (Inderal LA, Inderal XL, Innopran XL) are both prescription medications. Both medications may be used to prevent migraines but they also have several different uses. Topiramate is an antiepileptic used to control seizures, while propranolol used for high blood pressure and chronic chest pain, among other conditions. Topiramate is available in various forms, including tablets, capsules, and a liquid solution, and can be taken once or twice daily. Propranolol comes in immediate-release and extended-release forms, with dosing ranging from once to four times daily depending on the condition being treated. Topiramate can cause side effects like difficulty thinking clearly, kidney stones, and serious eye problems, whereas propranolol can cause higher risk or worsening of heart failure, serious skin reactions, and may hide symptoms of low blood sugar or overactive thyroid. Neither medication should be stopped suddenly, as it can raise your risk of a heart attack or stroke with propranolol and risk of seizures with topiramate. Additionally, both medications have generic versions available, making them more affordable.
