Key takeaways
Topiramate (Topamax) and gabapentin (Neurontin) are both antiepileptic medications, but they have different uses and dosing schedules. Topiramate is used to treat various types of seizures and to prevent migraines, while gabapentin is used for nerve pain from shingles and as an add-on treatment for partial seizures. Topiramate is available in both immediate-release and extended-release forms, and it can be taken once or twice daily. In contrast, gabapentin is typically taken three times a day and available as pills and a liquid. Topiramate can cause side effects like kidney stones and serious eye problems, whereas gabapentin can cause severe allergic reactions and cause dangerously slow breathing (respiratory depression). Additionally, gabapentin is controlled in some states due to its potential for misuse. Both medications are available in generic forms, making them more affordable options.
