Key takeaways
Methyltestosterone (Methitest) and testosterone gel (AndroGel) are both used to treat low testosterone in males, but they have some key differences. Methyltestosterone is taken orally, while testosterone gel is applied topically to the skin. Methyltestosterone can also be used to treat breast cancer in females, whereas testosterone gel is only approved for low testosterone in males. Methyltestosterone has a higher risk of causing serious liver damage, while testosterone gel has a higher risk of accidental transfer to others through skin contact. Methyltestosterone and testosterone gel are both available in a generic forms, making them less expensive. Both medications carry risks of misuse, dependency, and serious side effects like heart attack and stroke, but testosterone gel is noted to have a lower risk of heart conditions compared to methyltestosterone.
