Key takeaways
Methyltestosterone (Methitest) and Testopel (testosterone pellets) are both used to treat low testosterone and delayed puberty in males, but they have some key differences. Methyltestosterone can also be used to treat breast cancer in females. Methyltestosterone is taken orally in pill form, while Testopel is implanted under the skin as pellets. Methyltestosterone is available in a generic form, making it less expensive, whereas Testopel is only available as a brand medication and might be more costly. Testopel pellets are long-acting and need to be implanted every 3 to 6 months, which requires a minor surgical procedure lasting about 15 minutes. On the other hand, methyltestosterone is easier to take but can cause serious liver damage with long-term use. Both medications can cause side effects like enlargement of male breasts and acne, but Testopel also carries risks of infection at the implantation site and the pellets coming out of the skin. Neither medication is recommended for men with breast or prostate cancer nor women who are pregnant or may become pregnant.
