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Compare Methyltestosterone vs. Androgel

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Methyltestosterone (Methitest) and testosterone gel (AndroGel) are both used to treat low testosterone in males, but they have some key differences. Methyltestosterone is taken orally, while testosterone gel is applied topically to the skin. Methyltestosterone can also be used to treat breast cancer in females, whereas testosterone gel is only approved for low testosterone in males. Methyltestosterone has a higher risk of causing serious liver damage, while testosterone gel has a higher risk of accidental transfer to others through skin contact. Methyltestosterone and testosterone gel are both available in a generic forms, making them less expensive. Both medications carry risks of misuse, dependency, and serious side effects like heart attack and stroke, but testosterone gel is noted to have a lower risk of heart conditions compared to methyltestosterone.

  • Methyltestosterone (Methitest)
    Testosterone gel
  • Methyltestosterone (Methitest)
    Testosterone gel

  • Summary of Methyltestosterone vs. Androgel

    Summary for Testosterone replacement
    Prescription only

    Methyltestosterone (Methitest) is a pill form of testosterone used for testosterone replacement therapy (TRT) in males with low testosterone levels. It's also used to treat females with breast cancer that has spread to other parts of the body. The medication comes as a tablet or capsule and is typically taken by mouth once a day. Your dosage will depend on your condition and how you respond to treatment. Possible side effects include nausea, acne, and headaches.

    Summary for Testosterone replacement
    Prescription only

    Testosterone gel is used to treat low testosterone in adult males. It's convenient to use because you only have to apply it to your skin once a day. But compared to other forms of testosterone, there's a higher risk of exposing others to the medication through skin-to-skin contact.

  • Indications of Methyltestosterone vs. Androgel

    Indications for

    Males

    •Low testosterone (hypogonadism)
    •Delayed puberty

    Females

    •Breast cancer that has spread to other parts of the body
    Indications for
    •Low testosterone (hypogonadism)

  • Pros and Cons of Methyltestosterone vs. Androgel

    Pros and Const for Testosterone replacement
    Pros
    •Is a pill taken by mouth
    •Restores healthy testosterone levels in men
    •Supports male development during puberty
    Cons
    •Risk of liver problems with long-term use
    •Potential for serious heart problems and blood clots
    •Risk of misuse and dependence since it's a controlled substance
    Pros and Const for Testosterone replacement
    Pros
    •Works well to replace testosterone in your body
    •Applied once a day to your skin, so it's easy to use
    •Available in tubes, packets, or as a pump
    •Some brand names are available as lower-cost generics
    Cons
    •Can cause skin irritation
    •Need to avoid skin-to-skin transfer to other people
    •Need to wait hours before you can shower, swim, or bathe
    •Have to follow specific instructions on where and how it can be applied

  • Common Side Effects of Methyltestosterone vs. Androgel

    Common Side Effects for

    Males

    •Breast enlargement
    •Acne

    Females

    •Deeper voice
    •Acne
    •Missed or irregular menstrual periods
    •Increased facial and body hair
    Common Side Effects for
    •Skin irritation
    •Skin rash
    •Itchiness
    •High red blood cell count
    •Enlarged prostate
    •Acne

  • Warnings of Methyltestosterone vs. Androgel

    Common Side Effects for
    •Liver problems
    •Risk of blood clots, including heart attack or stroke
    •Potential for misuse, dependency, and addiction
    •Swelling in the legs or arms (edema)
    •High calcium in the blood
    •Fast bone maturation in children
    Common Side Effects for
    •Early puberty or development of male features
    •High red blood cell count and blood clots
    •Heart attack and stroke
    •Potential for misuse, addiction, and dependency
    •Worsening symptoms of enlarged prostate and prostate cancer
    •Liver problems
    •Swelling in the arms and legs (edema)
    •Breathing problems during sleep (sleep apnea)
    •High calcium in the blood

  • Prices with our coupons for Methyltestosterone vs. Androgel

    Learn more about Methyltestosterone
    Learn more about Testosterone gel

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