Key takeaways
Testosterone gel (Testim, AndroGel, Fortesta, Vogelxo) and testosterone enanthate (Delatestryl) are both used to treat low testosterone in males, but they differ in their forms and administration. Testosterone gel is applied topically to the skin once a day, while testosterone enanthate is given as an intramuscular injection every 2 to 4 weeks. The gel can be convenient but carries a risk of transferring the medication to others through skin contact, which can cause unwanted side effects in children and females. On the other hand, testosterone enanthate is administered by a healthcare professional and has a longer duration of action, but it can cause pain and swelling at the injection site. Testosterone enanthate is also FDA-approved for treating delayed puberty in males and metastatic breast cancer in females, whereas testosterone gel is not. Both medications have generic forms available, making them more affordable options. However, testosterone enanthate contains sesame oil, which may not be suitable for those with sesame allergies.
