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Compare Fluoxymesterone vs. Depo-Testosterone

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Androxy (fluoxymesterone) and Depo-Testosterone (testosterone cypionate) are both used to treat low testosterone levels in males, but they have some key differences. Androxy, an oral androgen, has been discontinued in the United States and is no longer available. In contrast, Depo-Testosterone is an injectable form of testosterone that is still available by prescription. Depo-Testerone is typically administered into the muscle every 2 to 4 weeks, which can be used at home with proper training. Depo-Testosterone has a broader range of serious side effects, including risks of heart attack, stroke, and liver damage, especially if misused. Androxy also had potential for abuse and dependence, but its discontinuation limits its current use.

  • Androxy (fluoxymesterone)
    Testosterone cypionate (Depo-Testosterone)
  • Androxy (fluoxymesterone)
    Testosterone cypionate (Depo-Testosterone)

  • Summary of Fluoxymesterone vs. Depo-Testosterone

    Summary for Androgen

    Androxy (fluoxymesterone) is a medication used for treating conditions caused by low testosterone in males. It is also used to treat breast cancer in females. Androxy (fluoxymesterone) is no longer available in the United States because it was discontinued.

    Summary for Testosterone replacement
    Prescription only

    Testosterone cypionate (Depo-Testosterone) is an injectable form of testosterone that’s used to treat low testosterone in adult males. It's injected into your buttock muscle and lasts for a long time, so it only needs to be used once or twice a month. But it might raise the risk of serious side effects including heart attack and stroke, especially if misused.

  • Indications of Fluoxymesterone vs. Depo-Testosterone

    Indications for
    Indications for
    •Low testosterone (hypogonadism)

  • Pros and Cons of Fluoxymesterone vs. Depo-Testosterone

    Pros and Const for Androgen
    Pros
    Cons
    Pros and Const for Testosterone replacement
    Pros
    •Only needs to be used once every 2 to 4 weeks
    •Can be injected at home
    •Comes in a vial that can be used for more than one dose, meaning fewer trips to the pharmacy
    •Available in as a lower-cost generic
    Cons
    •Risk of misuse, addiction, and dependency
    •Might raise the risk of serious side effects like heart attack and stroke if misused
    •Needs to be injected into the buttock muscle
    •Only available as an injection

  • Common Side Effects of Fluoxymesterone vs. Depo-Testosterone

    Common Side Effects for
    Common Side Effects for
    •Enlargement of male breasts
    •Acne
    •Pain at the injection site

  • Warnings of Fluoxymesterone vs. Depo-Testosterone

    Common Side Effects for
    Common Side Effects for
    •Potential for misuse, addiction, and dependency
    •Heart attack and stroke risk
    •Blood clots
    •Liver problems
    •Use in people with an enlarged prostate
    •Swelling in the arms and legs (edema)
    •High calcium in the blood
    •Use in young children

  • Prices with our coupons for Fluoxymesterone vs. Depo-Testosterone

    Learn more about Androxy
    Learn more about Testosterone cypionate

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