Androxy (fluoxymesterone) and Striant (testosterone) are both medications used to treat low testosterone levels in males, but they have some differences. Androxy (fluoxymesterone) is an androgen that also treats breast cancer in females, while Striant (testosterone) is specifically a testosterone replacement therapy for males. Both medications are taken orally, but Striant is a buccal tablet placed over the upper gum, whereas Androxy is a standard oral tablet. Both medications have been discontinued in the United States, and it's unclear why they were discontinued. However, there are still many other testosterone replacement therapies available, such as Androgel and Depo-Testosterone. Both Androxy and Striant are controlled substances (Schedule III) due to their potential for abuse and dependence.