Key takeaways
Fluoxymesterone (Androxy) and testosterone undecanoate (Aveed) are both medications used to treat low testosterone levels in males. However, they differ in several ways. Fluoxymesterone has been discontinued in the United States. In contrast, Aveed is an injectable testosterone replacement therapy. Aveed must be administered by a healthcare professional due to potential serious side effects, such as pulmonary oil microembolism (POME) and severe allergic reactions, which require monitoring under a Risk Evaluation and Mitigation Strategy (REMS) program. Aveed is only available as a brand-name medication. Common side effects of Aveed include acne, injection site pain, and fatigue. Additionally, Aveed has specific drug interactions, such as with blood thinners, which require careful monitoring.
