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Compare Methyltestosterone vs. Aveed

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Methyltestosterone (Methitest) and Aveed (testosterone undecanoate) are both testosterone replacement therapies, but they have some key differences. Methyltestosterone is taken orally and is available in a generic form, while Aveed is an injectable medication that must be administered by a healthcare professional. Methyltestosterone is used to treat low testosterone in males, delayed puberty in males, and breast cancer in females, whereas Aveed is only used to treat low testosterone in adult males. Methyltestosterone can cause serious liver damage with long-term use, while Aveed has a high risk of causing serious lung problems and severe allergic reactions, requiring it to be administered under a drug safety program called Risk Evaluation and Mitigation Strategies (REMS). Additionally, Aveed is only available as a brand medication, which might make it more expensive compared to the generic form of methyltestosterone. Both medications are both categorized as controlled medications, meaning that they have risks of misuse, dependency, and serious side effects.

  • Methyltestosterone (Methitest)
    aveed (testosterone undecanoate)
  • Methyltestosterone (Methitest)
    aveed (testosterone undecanoate)

  • Summary of Methyltestosterone vs. Aveed

    Summary for Testosterone replacement
    Prescription only

    Methyltestosterone (Methitest) is a pill form of testosterone used for testosterone replacement therapy (TRT) in males with low testosterone levels. It's also used to treat females with breast cancer that has spread to other parts of the body. The medication comes as a tablet or capsule and is typically taken by mouth once a day. Your dosage will depend on your condition and how you respond to treatment. Possible side effects include nausea, acne, and headaches.

    Summary for Testosterone replacement
    Prescription only

    Aveed (testosterone undecanoate) is an injectable testosterone that’s used to treat low testosterone in adult males. It's an FDA-approved testosterone replacement therapy that must be injected by a healthcare professional due to possible allergic reactions and a serious warning called pulmonary oil microembolism (POME), which causes symptoms such as coughing, chest pain, and trouble breathing. Initially, you'll receive the first two injections a month apart, then an injection every 10 weeks after that. Common side effects include acne, pain at the injection site, and fatigue.

  • Indications of Methyltestosterone vs. Aveed

    Indications for

    Males

    •Low testosterone (hypogonadism)
    •Delayed puberty

    Females

    •Breast cancer that has spread to other parts of the body
    Indications for
    •Low testosterone (also called hypogonadism)

  • Pros and Cons of Methyltestosterone vs. Aveed

    Pros and Const for Testosterone replacement
    Pros
    •Is a pill taken by mouth
    •Restores healthy testosterone levels in men
    •Supports male development during puberty
    Cons
    •Risk of liver problems with long-term use
    •Potential for serious heart problems and blood clots
    •Risk of misuse and dependence since it's a controlled substance
    Pros and Const for Testosterone replacement
    Pros
    •Works well to replace testosterone in your body
    •Can be given every 10 weeks (after the first 2 injections)
    •No accidental testosterone exposure to another person through skin-to-skin contact like testosterone gels
    Cons
    •Only available through a REMS program because of life-threatening side effects
    •Must be injected by your prescriber, so it can't be given at home
    •Only available as a brand-name medication

  • Common Side Effects of Methyltestosterone vs. Aveed

    Common Side Effects for

    Males

    •Breast enlargement
    •Acne

    Females

    •Deeper voice
    •Acne
    •Missed or irregular menstrual periods
    •Increased facial and body hair
    Common Side Effects for
    •Acne (5%)
    •Injection site pain (5%)
    •Rise in prostate-specific antigen (PSA, 5%)
    •Rise in estrogen levels (3%)
    •Tiredness (2%)
    •Irritability (2%)
    •Trouble sleeping (insomnia, 2%)
    •Mood swings (2%)

  • Warnings of Methyltestosterone vs. Aveed

    Common Side Effects for
    •Liver problems
    •Risk of blood clots, including heart attack or stroke
    •Potential for misuse, dependency, and addiction
    •Swelling in the legs or arms (edema)
    •High calcium in the blood
    •Fast bone maturation in children
    Common Side Effects for
    •Pulmonary oil microembolism (POME) and severe allergic reactions
    •Prostate problems
    •Risk of blood clots, including heart attack or stroke
    •Potential for misuse, dependency, and addiction
    •Liver problems
    •Swelling in the legs or arms (edema)
    •Sleep apnea
    •High calcium in the blood

  • Prices with our coupons for Methyltestosterone vs. Aveed

    Learn more about Methyltestosterone
    Learn more about aveed

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