Key takeaways
Methyltestosterone (Methitest) and testosterone (Striant) are both testosterone replacement therapy medications used in males with low testosterone levels. They belong to the same drug class, but they have some differences. Methyltestosterone is available as a tablet or capsule taken by mouth. Striant was an orally disintegrating tablet, but it has been discontinued in the U.S. Methyltestosterone is also FDA-approved for treating delayed puberty in males and breast cancer in females. Methyltestosterone is available as a lower-cost generic, while testosterone (Striant) is no longer available. Common side effects of methyltestosterone include nausea, acne, and headaches, and it can cause serious liver problems, heart issues, and blood clots. Methyltestosterone can interact with blood thinners and insulin, so it's important to discuss all medications with your prescriber.
