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Lyrica vs. Conzip

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Lyrica (pregabalin) and tramadol are both prescription medications, but they are used for different purposes and belong to different drug classes. Lyrica is an antiepileptic medication that treats nerve pain from conditions like diabetes, shingles, and spinal cord injuries, as well as fibromyalgia and partial-onset seizures. It is available in both capsule and oral solution forms and is typically taken 2 or 3 times a day. Tramadol, on the other hand, is an opioid pain medication used when non-opioid medications aren't effective enough. It comes in immediate-release and extended-release forms, with the immediate-release taken every 4 to 6 hours and the extended-release taken once a day. While Lyrica can cause dizziness and drowsiness, tramadol has a higher risk of serious side effects like dangerously slow breathing and addiction. Additionally, tramadol is not recommended for children under 12 or for breastfeeding mothers; Lyrica is also not recommended for breastfeeding mothers and must be used with caution in those with a history of swelling or depression. Both medications require careful monitoring and should not be stopped abruptly to avoid withdrawal symptoms.

Pregabalin

(Lyrica)

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Tramadol

 

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Summary for Lyrica

Prescription only

Pregabalin (Lyrica) helps treat nerve pain and fibromyalgia in adults. It can also be taken with other medications to help treat certain seizures in people 1 month and older. Pregabalin (Lyrica) comes as a capsule and oral solution in both brand-name and generic versions. The dosage depends on what condition you're treating, but it's usually taken by mouth 2 or 3 times a day. Common side effects include feeling dizzy and drowsy. This medication is a controlled substance and has interactions, like with alcohol and benzodiazepines.

Indications for Lyrica

Pros and Cons for Lyrica

Pros

  • An option for relieving nerve pain caused by diabetes, shingles, and spinal cord injuries
  • Can take with other anti-seizure medications for partial-onset seizures in people as young as 1 month of age
  • Available in a capsule and liquid

Cons

  • Can cause dizziness and drowsiness
  • Can cause weight gain
  • Is a controlled substance, so there are some rules to follow to get it filled

Common Side Effects for Lyrica

  • Dizziness
  • Drowsiness
  • Headache
  • Weight gain

Warnings for Lyrica

  • Allergic reactions and severe swelling
  • Risk of suicidal thoughts and behavior
  • Higher risk of side effects if you stop taking the medication too suddenly or too fast
  • Slowed breathing
  • Dizziness, sleepiness, and trouble concentrating
  • Swelling of the arms or legs
  • Weight gain
  • Lower platelet levels
  • Possible risk of muscle breakdown

Summary for Conzip

Prescription only

Tramadol is an opioid pain medication used when non-opioid medications aren't working well enough to control pain. Compared to other opioids, tramadol might have a lower risk of misuse and dependency. But tramadol is a controlled substance and has a lot of potentially serious risks, so it must be used with caution.

Indications for Conzip

  • Pain that isn't relieved by non-opioid pain medications alone

Pros and Cons for Conzip

Pros

  • Extended-release tablets and ConZip capsules are taken once per day and last throughout the day.
  • Immediate-release tablets are available as a lower-cost generic.
  • Possible lower risk of misuse and dependency compared to other opioids

Cons

  • A controlled medication, so there are special requirements to get a prescription filled
  • Must slowly lower the dose to stop the medication after long-term use to avoid withdrawal symptoms
  • Can't use in some children due to higher risk of potentially severe and life-threatening side effects
  • Not recommended while breastfeeding

Common Side Effects for Conzip

  • Constipation (up to 46%)
  • Nausea (up to 40%)
  • Dizziness (up to 33%)
  • Headache (up to 32%)
  • Sleepiness (up to 25%)
  • Vomiting (up to 17%)

Warnings for Conzip

  • Potential for addiction and misuse
  • Dangerously slow breathing (respiratory depression)
  • Overdose
  • Harm to newborn babies
  • Drug interactions
  • Difficulty concentrating and extreme sleepiness
  • Serotonin syndrome
  • Seizures
  • Low blood pressure
  • Low adrenal hormone levels
  • Physical dependence and withdrawal
  • Low blood sodium levels

Prices with our coupons for Lyrica vs. Conzip

Price Card Drug Icon
Pregabalin60 capsules / 75mg
$13.43$40.85
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Tramadol60 tablets / 50mg
$11.42$22.11
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