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Latuda vs. Fanapt

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Latuda (lurasidone) and Fanapt (iloperidone) are both atypical antipsychotics used to treat schizophrenia, but they have some key differences. Latuda is available in both generic and brand forms, while Fanapt is available as a brand name and generic for schizophrenia only. Latuda is also approved for treating depression from bipolar disorder in both adults and children, whereas Fanapt is only approved for schizophrenia and bipolar disorder in adults. You take Latuda once a day, but Fanapt needs to be taken twice a day. Latuda is less likely to cause weight gain compared to other antipsychotics, while Fanapt can cause some weight gain, though it is generally less significant. Both medications can cause sleepiness and dizziness, but Latuda has a higher risk of causing movement problems like tardive dyskinesia. Fanapt requires a strict dosing schedule when you first start taking it, which can be inconvenient.

Latuda

(lurasidone)

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Iloperidone

(Fanapt)

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Summary for Latuda

Prescription only

Latuda, also known by its generic name lurasidone, is a type of atypical antipsychotic. It's used to treat schizophrenia in adults and teens. It can also help with depression from bipolar disorder in people 10 years and older. Latuda (lurasidone) comes as a tablet that you swallow whole once a day with food (at least 350 calories). The most common side effect is sleepiness. This medication isn't likely to cause weight gain. Latuda (lurasidone) is available as brand-name and generic versions.

Indications for Latuda

Pros and Cons for Latuda

Pros

Cons

  • Can take several weeks before you notice the full effects of the medication
  • Can make you feel sleepy
  • Can cause movement problems

Common Side Effects for Latuda

  • Sleepiness
  • Nausea
  • Movement problems (e.g., tremors, slow movement, stiff muscles)
  • Can't stay still (restlessness)

Warnings for Latuda

  • Risk of suicidal thoughts and behavior
  • Higher risk of death in older people with dementia-related psychosis
  • Neuroleptic malignant syndrome (NMS)
  • Trouble controlling muscle movements (tardive dyskinesia)
  • Changes in blood sugar levels, cholesterol, and weight
  • Low blood pressure and risk of falls
  • Trouble concentrating and extreme sleepiness
  • High prolactin levels
  • Lower white blood cell count (leading to possible risk of infection)
  • Seizures
  • Risk of manic episode
  • Higher risk of side effects in people with Parkinson's disease or Lewy body dementia

Summary for Fanapt

Prescription only

Iloperidone (Fanapt) is an atypical antipsychotic. Brand name Fanapt is FDA-approved for schizophrenia and bipolar disorder in adults. Generic iloperidone is currently only approved for schizophrenia. Iloperidone (Fanapt) comes as a tablet that's taken by mouth twice per day. Don't drink alcohol while taking iloperidone (Fanapt) because doing so can worsen some common side effects, like sleepiness and dizziness. Some people have reported weight gain while taking this medication.

Indications for Fanapt

Pros and Cons for Fanapt

Pros

  • Taken by mouth
  • Comes in many different strengths to make it easier to customize your dose
  • A starter pack is available for when you first start to help you figure out your dose.
  • Available as a lower-cost generic

Cons

  • Taken twice a day
  • Hasn't been studied in children
  • The dose needs to be slowly raised
  • Safety in pregnancy and breastfeeding isn't well-understood

Common Side Effects for Fanapt

Schizophrenia

  • Dizziness (up to 20%)
  • Sleepiness (up to 15%)
  • Fast heart rate (up to 12%)
  • Dry mouth (up to 10%)
  • Nausea (up to 10%)

Bipolar disorder

  • Fast heart rate (up to 23%)
  • Dizziness (up to 12%)

Warnings for Fanapt

  • Higher risk of death in older people with dementia-related psychosis
  • Life-threatening abnormal heart rhythm (QT prolongation)
  • Neuroleptic malignant syndrome
  • Weight gain, higher blood sugar, and higher cholesterol levels
  • Difficulty controlling body movements
  • Changes in blood pressure and higher risk of falls
  • Risk of infection (from low white blood cell count)
  • Seizures
  • High prolactin levels
  • Difficulty concentrating and extreme sleepiness
  • Prolonged and painful erection
  • Intraoperative floppy iris syndrome (IFIS)

Prices with our coupons for Latuda vs. Fanapt

Price Card Drug Icon
Lurasidone30 tablets / 40mg
$20.78$1,532.02
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Price Card Drug Icon
Fanapt60 tablets / 6mg
$2,200.38$2,826.22
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