Key takeaways
Latuda (lurasidone) and Abilify (aripiprazole) are both atypical antipsychotics used to treat mental health conditions, but they have some differences. Latuda is used for schizophrenia and bipolar depression, while Abilify treats schizophrenia, bipolar I disorder, depression (as an add-on), Tourette syndrome, and irritability associated with autism. Latuda is taken once daily as a tablet, whereas Abilify is available in multiple forms, including tablets, oral solutions, and orally disintegrating tablets. Latuda is less likely to cause weight gain compared to other antipsychotics, while Abilify has a lower risk of weight gain but can still cause it. Common side effects of Latuda include sleepiness and nausea, while Abilify often causes headaches, agitation, and trouble sleeping. Both medications can cause serious side effects like neuroleptic malignant syndrome and movement problems, but Abilify also has a risk of impulse-control issues.
