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Isordil vs. Digoxin

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Isosorbide dinitrate (Isordil) and digoxin (Lanoxin) are both medications used to treat heart conditions, but they work in different ways and are used for different purposes. Isosorbide dinitrate is a vasodilator that helps relieve chest pain (angina) by relaxing blood vessels, making it easier for your heart to pump blood. It is available in both short-acting and long-acting forms, with the short-acting version available as a generic. Common side effects include headaches and dizziness. On the other hand, digoxin is an antiarrhythmic medication used to treat heart failure and atrial fibrillation (AFib) by making your heart pump more strongly and slowing down its electrical activity. Digoxin is available as a lower-cost generic but requires regular blood tests to monitor for potential toxicity, which can cause serious side effects like abnormal heart rhythms and vision changes. While isosorbide dinitrate can lower blood pressure, digoxin does not typically affect blood pressure, making it suitable for people with lower blood pressure. Both medications require careful adherence to dosing schedules to avoid complications.

Isosorbide dinitrate

(Isordil)

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Digoxin

(Lanoxin)

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Summary for Isordil

Prescription only

Isosorbide dinitrate (Isordil) is good for a specific type of chest pain (called angina), but it can cause headaches after you take it.

Indications for Isordil

  • Chest pain caused by angina

Pros and Cons for Isordil

Pros

  • Good at relieving chest pain caused by heart disease
  • Short-acting tablet is available as a generic version, making it less expensive

Cons

  • Has to be taken on a very specific schedule for the medication to work best
  • Daily headaches are a common side effect.
  • Can cause dizziness, especially when you change positions
  • Interacts with erectile dysfunction medications
  • Long-acting capsule is available as brand name only, making it more expensive

Common Side Effects for Isordil

  • Headache
  • Dizziness

Warnings for Isordil

  • LOW BLOOD PRESSURE
  • TOLERANCE

Summary for Digoxin

Prescription only

Digoxin (Lanoxin) is an antiarrhythmic medication used to treat heart failure and atrial fibrillation (AFib) in adults and children. It's taken by mouth typically once or twice daily, but the specific dosage will depend on several things like your age, weight, and blood digoxin levels. Side effects include changes in vision, stomach upset, and dizziness. There's also a risk of digoxin toxicity, which means having too much of the medication in your body. This can lead to severe side effects such as vision changes and changes to the heart rhythm.

Indications for Digoxin

Pros and Cons for Digoxin

Pros

  • Can be used in young children to treat heart failure
  • Doesn't affect blood pressure much
  • Available as a lower-cost generic

Cons

  • Can cause serious and potentially life-threatening side effects if medication levels in the blood are too high
  • Need to get regular blood tests during treatment
  • Interacts with many medications

Common Side Effects for Digoxin

  • Changes in heart rate
  • Nausea
  • Vomiting
  • Diarrhea
  • Reduced appetite

Warnings for Digoxin

  • Abnormal heart rhythm
  • Digoxin toxicity
  • Worsening heart conditions
  • Less efficacy in people with low calcium levels
  • Different responses in people with thyroid and metabolism problems

Prices with our coupons for Isordil vs. Digoxin

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Isosorbide Dinitrate90 tablets / 20mg
$31.55$81.53
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Digoxin90 tablets / 125mcg
$24.00$24.00
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