Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Hydralazine (generic only) and Nitroglycerin (Nitrostat) are both medications used to manage heart-related conditions, but they work differently and are used for different purposes. Hydralazine is a vasodilator that helps lower blood pressure by relaxing blood vessels. It's typically taken multiple times a day and is often used when other blood pressure medications aren't effective. Common side effects include headache, stomach upset, and a fast heart rate. On the other hand, Nitroglycerin is a nitrate used to prevent and treat angina (chest pain) by increasing blood flow to the heart. It works quickly, within 1 to 3 minutes, and is taken as a tablet placed under the tongue or against the cheek. Nitroglycerin can cause low blood pressure and headaches, and you should avoid alcohol while taking it. Unlike Hydralazine, Nitroglycerin is available in both brand-name and generic forms.
Hydralazine
Nitroglycerin (Nitrostat)
Hydralazine
Nitroglycerin (Nitrostat)
Summary of Hydralazine vs. Nitrostat
Summary for Vasodilator
Prescription only
Hydralazine is a medication that's used to lower blood pressure. It's less commonly used for blood pressure, but it can be helpful when other first-choice medications aren't working. The dosage varies quite a bit; not everyone will take the same dose, but this medication is typically taken a few times a day. Common side effects include headache, stomach upset, and a fast heart rate. Hydralazine is available as a lower-cost generic tablet (there's no brand-name version).
Summary for Nitrate
Prescription only
Nitroglycerin (Nitrostat) is a fast-acting medication that’s used to prevent and treat angina (or chest pain). It helps with angina by allowing more blood to flow to the heart. Nitroglycerin (Nitrostat) is a tablet that’s placed under your tongue or against the cheek inside your mouth. Side effects include low blood pressure and headache. Nitroglycerin (Nitrostat) is available as a brand-name and generic medication.