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Indocin vs. Celebrex

Indomethacin (Indocin) suppository is an NSAID that's used to treat different types of arthritis and conditions that cause pain in the shoulder. It helps lower inflammation and relieve pain. As a suppository, it's inserted into the rectum, typically 2 to 4 times a day depending on what condition the medication is being used to treat. Side effects might include headache and stomach upset. Unlike other NSAIDs, indomethacin (Indocin) suppository isn't available over-the-counter and requires a prescription from your healthcare provider.

• Moderate-to-severe rheumatoid arthritis, including flare-ups
• Moderate-to-severe ankylosing spondylitis
• Moderate-to-severe osteoarthritis
• Shoulder pain caused by bursitis or tendonitis
• Gouty arthritis

Note: The side effects listed here are for indomethacin capsules. Side effects for the suppositories might differ.

• Headache
• Dizziness
• Nausea
• Stomach upset

• Stomach bleeding and ulcers
• Heart attack and stroke
• High blood pressure and heart failure
• Liver problems
• Kidney damage and high potassium levels
• Severe allergic reactions
• Severe asthma attack
• Worsening of nervous system and mental health problems
• Harm to unborn babies

Celecoxib, also known by the brand name Celebrex, is a prescription pain medication that's used to temporarily relieve aches and pains from certain conditions, such as different types of arthritis. Celebrex (celecoxib) is a non-steroidal anti-inflammatory drug (NSAID), but it has a lower risk of causing stomach upset than other medications in its drug class, such as naproxen. The dosage for Celebrex (celecoxib) is typically once or twice a day. It's recommended to avoid taking this medication with alcohol since it can raise your risk for stomach bleeding. Other side effects include headache, indigestion, and diarrhea.

• Osteoarthritis (OA)
• Rheumatoid arthritis (RA)
• Juvenile rheumatoid arthritis (JRA)
• Ankylosing spondylitis (AS)
• Sudden pain
• Menstrual cramps

Adults

• Headache (16%)
• Indigestion (9%)
• Upper respiratory infection (8%)
• Diarrhea (6%)
• Sinus infection (congestion, runny nose; 5%)
• Belly pain (4%)

Children

• Headache (13%)
• Fever (8%)
• Belly pain (4-8%)
• Cough (7%)
• Nausea (7%)
• Diarrhea (5%)
• Common cold (stuffy nose, sneezing; 5%)

• Heart attack and stroke
• Stomach bleeding and ulcers
• Liver problems
• High blood pressure and heart failure
• Kidney damage and high potassium levels
• Severe allergic reactions
• Severe asthma attack
• Harm to unborn babies