Key takeaways
Hydrochlorothiazide and Dutoprol (metoprolol succinate / hydrochlorothiazide) are both used to treat high blood pressure. They both contain hydrochlorothiazide, a diuretic that helps remove extra water and certain electrolytes to lower blood pressure. However, they differ in several ways. Hydrochlorothiazide is a standalone thiazide diuretic, while Dutoprol is a combination medication that also includes metoprolol succinate, a beta blocker that slows down your heart rate. Hydrochlorothiazide is available as a generic, lower-cost option, whereas Dutoprol was available only as a brand name medication, but has been discontinued and is no longer available in the United States. Hydrochlorothiazide is typically taken once daily, and its side effects include dizziness, increased urination, and sensitivity to sunlight. Dutoprol, when it was available, combined the effects of both medications, so side effects related to metoprolol, such as fatigue and slow heart rate, would also be a consideration.
