Glyburide vs. Miglitol for Diabetes Type 2: Important Differences and Potential Risks.

Glyburide

Miglitol

Summary for Glyburide

Prescription only

Glyburide is taken by mouth to lower blood sugar levels for people who have Type 2 diabetes. This medication isn't meant to be taken alone, but in addition to eating a healthy diet and engaging in regular exercise. Glyburide is typically taken once or twice daily, depending on your dose.

Indications for Glyburide

Type 2 diabetes

Pros and Cons for Glyburide

Pros

Usually taken only once daily with largest meal
Can lower A1C levels by 1.5%
Taken by mouth, so good option for people who don't like injections
Can be taken with some other blood sugar medications, such as metformin

Cons

Risk of low blood sugar (hypoglycemia), especially if you have kidney or liver problems
More likely to cause low blood sugar than other blood sugar medications, such as metformin
Can cause some weight gain
Not approved for Type 1 diabetes

Common Side Effects for Glyburide

Feeling bloated
Nausea
Heartburn

Warnings for Glyburide

Low blood sugar (hypoglycemia)
Possible risk of heart problems
Breakdown of red blood cells

Summary for Miglitol

Prescription only

Miglitol is a medication that's used together with diet and exercise to help control blood sugar in adults with Type 2 diabetes. This medication is taken by mouth, typically 3 times a day with the first few bites of each meal. Miglitol isn't as commonly used as other diabetes medications since it can lead to some unpleasant side effects like gas and diarrhea. But it's less likely to cause hypoglycemia when used on its own. It's only available as the generic name miglitol since the brand name Glyset is no longer available.

Indications for Miglitol

Type 2 diabetes in adults

Pros and Cons for Miglitol

Pros

Not likely to cause weight gain, instead it might cause weight loss
Helps control blood sugar levels after each meal
Low risk of low blood sugar when used alone
Can be used with other diabetes medications

Cons

Must be taken multiple times a day
Side effects include diarrhea, gas, and stomach pain
Not recommended for people with severe kidney problems
Typically not considered a first-choice treatment option

Common Side Effects for Miglitol

Passing gas (42%)
Diarrhea (29%)
Stomach pain (12%)

Warnings for Miglitol

Low blood sugar when taken together with other diabetes medications
Kidney problems causing medication buildup
Losing control of blood sugar

Prices with our coupons for Glyburide vs. Miglitol

Glyburide180 tablets / 5mg

$25.93$71.02

Get free coupons

More Information

Miglitol100 tablets / 25mg

$57.88$207.93

Get free coupons

More Information

Browse medications by letter

Show All

Browse prescription and over-the-counter medications from A to Z, compare drug prices, and start saving.

Compare
Glyburide vs. Miglitol

Glyburide

Miglitol

Summary for Glyburide

Indications for Glyburide

Pros and Cons for Glyburide

Pros

Cons

Common Side Effects for Glyburide

Warnings for Glyburide

Summary for Miglitol

Indications for Miglitol

Pros and Cons for Miglitol

Pros

Cons

Common Side Effects for Miglitol

Warnings for Miglitol

Prices with our coupons for Glyburide vs. Miglitol

Compare other Diabetes Type 2 drugs

Browse medications by letter

Good news for your inbox

Glyburide

Miglitol

Summary for Glyburide

Indications for Glyburide

Pros and Cons for Glyburide

Pros

Cons

Common Side Effects for Glyburide

Warnings for Glyburide

Summary for Miglitol

Indications for Miglitol

Pros and Cons for Miglitol

Pros

Cons

Common Side Effects for Miglitol

Warnings for Miglitol