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Farxiga vs. Glucotrol

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Farxiga (dapagliflozin) and Glucotrol (glipizide) are medications used to treat Type 2 diabetes, but they some differences between them. Farxiga helps lower blood sugar by causing your body to get rid of excess sugar through your urine. It also has benefits for heart failure and chronic kidney disease (CKD). On the other hand, Glucotrol works to lower blood sugar by telling your pancreas to release more insulin. Farxiga is taken once daily and only available as a brand medication, while Glucotrol can be taken once or twice daily and is available as a lower-cost generic. Farxiga has a lower risk of causing low blood sugar but can increase the risk of urinary tract infections and dehydration. In contrast, Glucotrol has a higher risk of causing low blood sugar (hypoglycemia) and can lead to weight gain.

Farxiga

(dapagliflozin)

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Glipizide

 

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Summary for Farxiga

Prescription only

Farxiga, the brand name for dapagliflozin, is used together with a nutritious diet and exercise plan to lower blood sugar levels in people 10 years and older with Type 2 diabetes. It can also help lower the risk of serious complications, hospitalization, and death in certain adults with heart failure or chronic kidney disease (CKD). Farxiga (dapagliflozin) belongs to the drug class called sodium-glucose cotransporter 2 (SGLT2) inhibitors. It's taken by mouth once a day. Some side effects include yeast infections, urinating more often, and weight loss.

Indications for Farxiga

  • Type 2 diabetes (in addition to diet and exercise) in people age 10 and over
  • Lowering the risk of hospitalization for heart failure in adults with Type 2 diabetes and heart disease
  • Lowering the risk of hospitalization and death due to heart problems in people with heart failure
  • Lowering the risk of worsening kidney problems, hospitalization for heart failure, and death due to heart problems in adults with chronic kidney disease (CKD)

Pros and Cons for Farxiga

Pros

  • Taken only once daily
  • Low risk of causing low blood sugar when taken by itself
  • Can take with other diabetes medications

Cons

Common Side Effects for Farxiga

Warnings for Farxiga

  • Ketoacidosis
  • Low fluids in the body (leading to low blood pressure or dehydration)
  • Genital and urinary tract infections
  • Low blood sugar (hypoglycemia) when used with other diabetes medications

Summary for Glucotrol

Prescription only

Glipizide is a sulfonylurea medication used to treat Type 2 diabetes in adults. It lowers blood sugar levels by telling your pancreas to release more insulin. Glipizide is taken by mouth, typically once or twice daily. Some side effects of this medication include dizziness and diarrhea. Taking glipizide can also put you at risk for dangerously low blood sugar, so it's important to take this medication with meals.

Indications for Glucotrol

Pros and Cons for Glucotrol

Pros

  • Taken by mouth
  • Extended-release tablets taken once daily
  • Available as a lower-cost generic medication

Cons

  • Raises your risk for low blood sugar levels (hypoglycemia)
  • Need to take with meals or 30 minutes before a meal
  • Can cause some weight gain as a side effect

Common Side Effects for Glucotrol

  • Dizziness (7%)
  • Diarrhea (5%)
  • Nervousness (4%)
  • Tremor (4%)
  • Passing gas (3%)
  • Low blood sugar levels (3%)

Note: Side effects were reported by people who took glipizide ER (Glucotrol XL) in clinical studies.

Warnings for Glucotrol

  • Low blood sugar levels
  • Risk of low red blood cell count (hemolytic anemia)
  • Possible risk of serious heart problems
  • Risk of harm in people with certain stomach problems (extended-release tablets)

Prices with our coupons for Farxiga vs. Glucotrol

Price Card Drug Icon
Farxiga30 tablets / 10mg
$288.00$438.23
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Glipizide90 tablets / 10mg
$12.83$12.83
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