Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Phenytoin (Dilantin) and fosphenytoin (Cerebyx) are both antiepileptic medications used to treat and prevent various types of seizures, including those during and after brain surgery, but they have some key differences. Phenytoin is available in capsules, chewable tablets, liquid, and injection, while fosphenytoin is an injectable medication typically given by a healthcare professional. Both are available as low-cost generics. Fosphenytoin is converted into phenytoin in the body and used when you can't take oral medications. Because of this, side effects are similar between both medications and include dizziness, sleepiness, and uncontrolled eye movements. Both medications can cause serious side effects, including heart problems and severe allergic reactions, but fosphenytoin has additional risks like "purple glove syndrome," where there is purple-bluish discoloration, swelling, and pain at the injection site.
Phenytoin (Dilantin)
Fosphenytoin (Cerebyx)
Phenytoin (Dilantin)
Fosphenytoin (Cerebyx)
Summary of Dilantin vs. Cerebyx
Summary for Antiepileptic
Prescription only
Phenytoin (Dilantin) is an antiepileptic medication used to treat and prevent seizures in adults and children. It comes in a capsule, chewable tablet, and liquid suspension that you take by mouth. The dose depends on your age, weight, and how well your seizures are controlled. Common side effects include trouble with coordination, unpredictable eye movements, and sleepiness. You’ll need regular blood tests to avoid toxicity, which is when the amount of medication in your body is too high and could be dangerous.
Summary for Antiepileptic
Prescription only
Fosphenytoin (Cerebyx) is an injectable medication used to treat and prevent seizures in both children and adults. This medication has many risks and possible side effects, including uncontrolled eye movements, dizziness, and trouble moving your muscles. Fosphenytoin (Cerebyx) is typically given by a healthcare provider.