Cannabinoids are medications based on the active ingredients found in the cannabis plant. They're used to treat nausea and vomiting caused by chemotherapy, certain types of epilepsy, and loss of appetite caused by chronic conditions. Cannabinoids work by interacting with the endocannabinoid system in your body. Examples include dronabinol (Marinol), cannabidiol (Epidiolex), and nabilone (Cesamet).