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Fluticasone / Salmeterol Coupon - Fluticasone / Salmeterol 0.45g of 113mcg/14mcg respiclick inhaler

fluticasone / salmeterol

Generic Airduo
Used for Asthma, COPD
Used for Asthma, COPD

Airduo is a combination inhaler. This medication contains fluticasone (an inhaled corticosteroid) and salmeterol (a long-acting beta agonist, or LABA). AirDuo (​​fluticasone / salmeterol) is used as maintenance treatment of asthma in people ages 12 years and older. It's inhaled by mouth twice daily. Some of the more common side effects of AirDuo (​​fluticasone / salmeterol) include upper respiratory tract infections, sore throat, and headaches. This medication is available as brand name Airduo RespiClick, as well as the smart inhaler Airduo Digihaler.

Last reviewed on January 2, 2024
basics-icon

What is AirDuo (​​fluticasone / salmeterol)?

What is AirDuo (​​fluticasone / salmeterol) used for?

  • Maintenance treatment of asthma in adults and children ages 12 years and older

How AirDuo (​​fluticasone / salmeterol) works

AirDuo (​​fluticasone / salmeterol) is a combination of two medications that work together to help treat asthma and COPD symptoms.

  • Fluticasone is an inhaled corticosteroid. The exact way that it works to treat asthma isn't well-understood. But it's thought to work directly in your lungs to lower inflammation and swelling, thus making it easier for you to breathe.

  • Salmeterol is a long-acting beta agonist. It works by relaxing the muscles in your lungs to open up your airways, making it easier to breathe.

Are you looking for information on Wixela (fluticasone / salmeterol) or Advair (fluticasone / salmeterol) instead?

Drug Facts

Common BrandsAirDuo RespiClick, Airduo Digihaler
Drug ClassICS / LABA combo
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only
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Avg retail price
$128.72(save 11.31%)
GoodRx discount
$114.17
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basics-icon

What are the side effects of AirDuo (​​fluticasone / salmeterol)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Runny nose and sore throat (up to 9%)
  • Headache (up to 6%)

Other Side Effects

  • Cough
  • Back pain
  • Oral thrush (fungal infection in the mouth)

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Serious allergic reaction: hives, swelling of your face, lips, or tongue, difficulty breathing
  • Sudden narrowing of your airways: difficulty breathing, wheezing, chest pain or tightness, cough
  • Heart problems: dizziness, fatigue, tremor, nausea, rapid heartbeat, weakness, or difficulty sleeping

Source: DailyMed

The following side effects have also been reported

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Flu-like symptoms—fever, chills, muscle pain, cough, headache, fatigue
  • Heart rhythm changes—fast or irregular heartbeat, dizziness, feeling faint or lightheaded, chest pain, trouble breathing
  • Increase in blood pressure
  • Low adrenal gland function—nausea, vomiting, loss of appetite, unusual weakness or fatigue, dizziness
  • Muscle pain or cramps
  • Pain, tingling, or numbness in the hands or feet
  • Sinus pain or pressure around the face or forehead
  • Thrush—white patches in the mouth
  • Wheezing or trouble breathing that is worse after use

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

pros-and-cons

Pros and cons of AirDuo (​​fluticasone / salmeterol)

thumbs-up

Pros

Works well to lower the risk of asthma symptoms

Combines two medications into a single inhaler for convenience

Airduo Digihaler can be linked to a phone app that captures important information you can use to track treatment

thumbs-down

Cons

Not a rescue inhaler for treating sudden trouble breathing

Needs to be inhaled twice per day

Can't be used with a spacer

Not a good choice for people allergic to lactose

pharmacist-tips

Pharmacist tips for AirDuo (​​fluticasone / salmeterol)

pharmacist
  • Use AirDuo (​​fluticasone / salmeterol) twice daily at the same times every day. This medication works best if it's taken regularly every day.

    • Let your provider know if you're severely allergic to milk proteins because AirDuo (​​fluticasone / salmeterol) contains lactose.

      • Make sure to rinse your mouth with water and spit after each time you use AirDuo (​​fluticasone / salmeterol). This helps prevent fungal infections in your mouth and throat (thrush).

        • If you have sudden trouble breathing during an asthma attack, use your rescue inhaler. AirDuo (​​fluticasone / salmeterol) won't treat an asthma attack as it's happening.

          • Call your provider if your breathing or peak flow meter results worsen. Also contact your provider if you're using your rescue inhaler more often than usual. These could be signs that your AirDuo (​​fluticasone / salmeterol) dose is too low, or you need another long-acting medication to help manage your asthma.

            • Don't start any new medications while you're taking AirDuo (​​fluticasone / salmeterol) without asking your provider or pharmacist first. AirDuo (​​fluticasone / salmeterol) can interact with other medications, such as blood pressure medications (e.g., beta blockers), tricyclic antidepressants, and certain water pills (diuretics). Your providers can check for interactions to make sure your medications are safe to take.

              • If you have Airduo Digihaler, it's recommended to download and use the Digihaler app. This app captures important information about your treatment, such as how well you're breathing in when you use the inhaler. But you don't need to use the app to use the Airduo Digihaler.

                • Store AirDuo (​​fluticasone / salmeterol) at room temperature in a dry place away from heat or sunlight. Keep unused inhalers in the original foil pouch.

                  Tips for using Airduo Digihaler or Airduo RespiClick:

                  • You don't need to prime or shake the AirDuo (​​fluticasone / salmeterol) inhaler before using it.

                    • When you're ready to take your dose, open the yellow cap until it clicks. This loads the dose. Hold the AirDuo (​​fluticasone / salmeterol) inhaler in an upright position. Then, breathe out as long as you can.

                      • To inhale, place your lips firmly around the mouthpiece and take a fast and deep breath. Try to hold your breath for up to 10 seconds or for as long as you comfortably can so that the medication can reach deep into your lungs. Close the yellow cap when finished. Then, rinse and spit with water.

                        • Never wash the AirDuo (​​fluticasone / salmeterol) inhaler. Instead, clean the mouthpiece every once in a while by wiping it with a dry cloth. Don't get water or moisture on or near the inhaler. Moisture can make the dry powder medication clump together and clog the inhaler.

                          faqs

                          Frequently asked questions about AirDuo (​​fluticasone / salmeterol)

                          How many puffs are in AirDuo (​​fluticasone / salmeterol)?
                          Both Airduo RespiClick and Airduo Digihaler contain 60 puffs, which lasts 30 days. Each inhaler has a dose counter on the back of the inhaler. It should say "60" for a new inhaler. Use this counter to keep track of when you need to get a refill.
                          What's the difference between Airduo Digihaler and Airduo Respiclick?
                          Both Airduo Digihaler and Airduo RespiClick are brands that contain the same active ingredients, fluticasone and salmeterol. The only difference is that the Airduo Digihaler is the "smart" version of the inhaler - it has sensors that can track and share data about your treatment to a phone app. You and your provider can use the data in the app to see how well you're treatments are going.
                          Can AirDuo (​​fluticasone / salmeterol) be used with a spacer?
                          No, neither Airduo RespiClick nor Airduo Digihaler can be used with a spacer.
                          Does AirDuo (​​fluticasone / salmeterol) have a steroid in it?
                          Yes. Airduo contains fluticasone, which is a steroid that lowers inflammation in the lungs. The other active ingredient, salmeterol, is a long-acting beta agonist that keeps your airways open. Both medications work together to make it easier for you to breathe.
                          Does AirDuo (​​fluticasone / salmeterol) cause weight gain?
                          Weight gain is a possible side effect of AirDuo (​​fluticasone / salmeterol), but it's rare. In general, corticosteroids (like fluticasone) can cause weight gain, especially if they're taken by mouth and over a longer period of time. But since the fluticasone in AirDuo (​​fluticasone / salmeterol) is inhaled, it's less likely to cause weight gain compared to oral steroids. Talk with your provider if you experience changes in weight while taking AirDuo (​​fluticasone / salmeterol).
                          How often can you use AirDuo (​​fluticasone / salmeterol)?
                          AirDuo (​​fluticasone / salmeterol) should be inhaled twice per day, about 12 hours apart, at the same times every day. This means AirDuo (​​fluticasone / salmeterol) should be taken even if you're not having trouble breathing. It's not an inhaler that's used as-needed. Only rescue inhalers, like albuterol (ProAir, Ventolin HFA), should be used as needed to treat sudden trouble breathing.
                          Is Airduo the same as Advair?
                          No, they're two different medications. Both Airduo and Advair are dry powder inhalers that contain the same active ingredients, fluticasone and salmeterol, but each brand contains a different amount of each ingredient per inhalation. Additionally, Advair is used for maintenance treatment of both COPD and asthma in people ages 4 years and up, whereas AirDuo (​​fluticasone / salmeterol) is used for maintenance treatment of asthma in people ages 12 years and up. Finally, the devices of each brand slightly differ from each other. Talk to your provider about which brand is right for you.
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                          warings-icon

                          What are the risks and warnings for AirDuo (​​fluticasone / salmeterol)?

                          AirDuo (​​fluticasone / salmeterol) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

                          risk-warning

                          Not for use in asthma attack or for worsening breathing

                          Don't use AirDuo (​​fluticasone / salmeterol) if you're experiencing an asthma attack because this medication won't provide immediate relief. Use a rescue inhaler, such as albuterol (Ventolin HFA), if you're having trouble breathing.

                          If you're using your rescue inhaler more often than usual, let your provider know because this could be a sign that your condition is getting worse. Don't use more doses AirDuo (​​fluticasone / salmeterol) than recommended because this won't improve your breathing. Rather, this can raise your risk for serious side effects, such as heart problems, tremors, and dizziness.

                          risk-warning

                          Fungal infection in the mouth

                          • Risk factor: Not rinsing and spitting after using AirDuo (​​fluticasone / salmeterol) | Weakened immune system from medical conditions or medications

                            AirDuo (​​fluticasone / salmeterol) includes a steroid medication (fluticasone). When inhaled, it can cause a fungal infection in your mouth and throat called thrush. To lower your risk for thrush, rinse your mouth with water and spit after each inhalation of AirDuo (​​fluticasone / salmeterol). If you develop thrush, your provider might prescribe you a medication to treat this condition and ask you to temporarily stop using AirDuo (​​fluticasone / salmeterol). Let your provider know if you notice symptoms of thrush, such as white patches in your mouth, cotton-like feeling in your mouth, pain while eating or swallowing, or loss of taste.

                            risk-warning

                            Narrowing of your airways (bronchospasm)

                            Inhaled medications, including AirDuo (​​fluticasone / salmeterol), can sometimes cause a muscle spasm in your lungs. This can lead to difficulty breathing, wheezing, cough, and chest discomfort. If you have a hard time breathing after inhaling AirDuo (​​fluticasone / salmeterol), use your rescue inhaler and get medical attention right away.

                            risk-warning

                            Higher risk of infections

                            Like all corticosteroid-containing medications, AirDuo (​​fluticasone / salmeterol) can weaken your immune system and raise your risk for infections, including upper respiratory infections and pneumonia. Your risk for infections is higher if you're also taking other medications that also weaken your immune system. If you're currently being treated for a serious infection, such as tuberculosis, let your provider know. They might need to consider a different medication for your condition until you get better. Let your provider know right away if you have symptoms of infections, such as fever, chills, body aches.

                            risk-warning

                            Altered stress hormone levels

                            • Risk factors: Using AirDuo (​​fluticasone / salmeterol) for a long time | Using too much AirDuo (​​fluticasone / salmeterol)

                              Use AirDuo (​​fluticasone / salmeterol) only as directed. Don't use more than the maximum number of inhalations each day. Using more doses of AirDuo (​​fluticasone / salmeterol) than recommended can cause more steroid to be absorbed into the body and you might experience symptoms such as higher blood sugar or blood pressure.

                              On the other hand, if you're transitioning to AirDuo (​​fluticasone / salmeterol) from oral steroids, you might experience symptoms of low steroid hormone, such as stomach pain, loss of appetite, and nausea. When you transition to AirDuo (​​fluticasone / salmeterol), your provider will work with you to lower your dose of oral steroids slowly over time to prevent these side effects.

                              risk-warning

                              Delayed growth in children

                              Children who use inhaled steroids, like AirDuo (​​fluticasone / salmeterol), might experience a delay in growth. To lower the risk of growth problems, your child's provider will only prescribe the lowest dose needed to help their condition. The provider will check your child's growth regularly while they're receiving this medication. If you're concerned about how AirDuo (​​fluticasone / salmeterol) might affect your child's growth, discuss with your child's provider to see if this medication is right for them.

                              risk-warning

                              Eye and vision problems

                              • Risk factors: History of glaucoma or cataracts

                                Though rare, people using inhaled steroids over a long period of time have reported having higher pressure in the eyes, glaucoma, and cataracts. Talk to your eye provider before using AirDuo (​​fluticasone / salmeterol) if you have glaucoma or cataracts because they might ask you to come in more often for eye exams. Also speak with them if you notice any changes to your vision while using the medication.

                                risk-warning

                                Heart problems

                                • Risk factors: High blood pressure | Heart failure | Heart rate or rhythm problems | Using more AirDuo (​​fluticasone / salmeterol) than recommended

                                  The salmeterol in Airduo might cause changes in your blood pressure, heart rate, and heart rhythm. But these side effects are typically unlikely to happen if you're taking the recommended dose of AirDuo (​​fluticasone / salmeterol). Your provider might ask you to regularly check your blood pressure and heart rate at home if you have high blood pressure or other heart problems. Don't use AirDuo (​​fluticasone / salmeterol) more often than recommended. If you find that you need to use AirDuo (​​fluticasone / salmeterol) more often, let your providers know so they can see if you need any changes to your treatment plan. Tell your provider if you have dizziness, fatigue, tremor, rapid heartbeat, or weakness after you use AirDuo (​​fluticasone / salmeterol).

                                  risk-warning

                                  Low potassium levels in the blood

                                  • Risk factors: Using AirDuo (​​fluticasone / salmeterol) too much

                                    AirDuo (​​fluticasone / salmeterol) can cause the potassium levels in your blood to drop too low. In most cases, this happens if you use more AirDuo (​​fluticasone / salmeterol) than recommended. Drops in blood potassium levels are typically mild and your levels should go back to usual with time. Sometimes, low potassium can cause tiredness, weakness, muscle cramps, a racing heart, and a "pins and needles" feeling in your hands and feet. Tell your provider if you experience any of these symptoms while you're using AirDuo (​​fluticasone / salmeterol). Also let your provider know if you need to use AirDuo (​​fluticasone / salmeterol) more often than instructed. Your treatment plan might need to be adjusted to better control your symptoms.

                                    risk-warning

                                    Allergic reactions

                                    Allergic reactions to AirDuo (​​fluticasone / salmeterol) are possible. These reactions can include life-threatening facial swelling, shock, and anaphylaxis (closing of the throat). Get medical attention right away if you notice hives, rash, red skin, swelling of the lips or tongue, or difficulty breathing after you use AirDuo (​​fluticasone / salmeterol).

                                    dosage

                                    AirDuo (​​fluticasone / salmeterol) dosage forms

                                    The average cost for 1 respiclick inhaler of 0.45g of 113mcg/14mcg of AirDuo (​​fluticasone / salmeterol) is $337.33 with a free GoodRx coupon. This is 30.53% off the average retail price of $485.59.
                                    respiclick inhaler
                                    Respiclick inhaler
                                    DosageQuantityPrice as low asPrice per unit
                                    0.45g of 55mcg/14mcg1 respiclick inhaler$114.17$114.17
                                    0.45g of 113mcg/14mcg1 respiclick inhaler$337.33$337.33
                                    0.45g of 232mcg/14mcg1 respiclick inhaler$127.99$127.99

                                    Typical dosing for AirDuo (​​fluticasone / salmeterol)

                                    Airduo Digihaler and Airduo Respiclick are available in 3 different strengths: 55 mcg/14 mcg (fluticasone / salmeterol), 113 mcg/14 mcg (fluticasone / salmeterol), and 232 mcg/14 mcg (fluticasone / salmeterol).

                                    • Your provider will determine your dose based on how severe your asthma is and what other medications you've taken. The typical dose is 1 inhalation by mouth twice daily.

                                    drug-cost

                                    How much does AirDuo (​​fluticasone / salmeterol) cost?

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                                    contraindications-icon

                                    AirDuo (​​fluticasone / salmeterol) contraindications

                                    Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because AirDuo (​​fluticasone / salmeterol) will not be safe for you to take.
                                    • Treatment of sudden, severe asthma attack

                                    • Allergy to fluticasone (inhaled corticosteroid) or salmeterol (long-acting beta agonist)

                                    • Allergy to lactose or milk proteins

                                    alternatives

                                    What are alternatives to AirDuo (​​fluticasone / salmeterol)?

                                    There are a number of medications that your doctor can prescribe in place of AirDuo (​​fluticasone / salmeterol). Compare a few possible alternatives below.
                                    AirDuo (​​fluticasone / salmeterol)
                                    Used for:
                                    • Maintenance treatment of asthma in adults and children ages 12 years and older

                                    $114.17 Lowest GoodRx priceView Prices
                                    Used for:
                                    • Maintenance treatment of asthma

                                    • Maintenance treatment of COPD

                                    $233.52 Lowest GoodRx priceView Prices
                                    latest news

                                    What is the latest news about AirDuo (​​fluticasone / salmeterol)?

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                                    AirDuo (​​fluticasone / salmeterol) images

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                                    This medicine is White Respiclick Inhaler.white - Fluticasone Propionate / Salmeterol 113mcg-14mcg / actuation Powder for Inhalation

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                                    References

                                    Best studies we found

                                    American Lung Association. (2023). Measuring your peak flow rate.

                                    MedlinePlus. (2016). Cushing's syndrome.

                                    National Institute of Diabetes and Digestive and Kidney Diseases. (2018). Symptoms & causes of adrenal insufficiency & Addison's disease.

                                    View All References (4)
                                    GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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