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Metronidazole Coupon - Metronidazole 500mg tablet

metronidazole

Generic Flagyl
Used for Amoebiasis, Bacterial Infection, Bacterial Vaginosis, Diarrhea, Gastrointestinal Infection, Lower Respiratory Infection, Meningitis, Parasitic Infection, Rosacea, Skin Infection

Metronidazole (Flagyl) is a nitroimidazole antibiotic that’s FDA-approved in humans. Veterinarians also prescribe this medication off-label to treat certain infections in dogs and cats. For pets, metronidazole is given by mouth, typically twice daily. Treatment usually lasts 5 to 7 days. Metronidazole comes as a tablet or capsule.Your veterinarian might recommend for you to go to a compounding pharmacy to have it made into a liquid that’s easier for your pet to take. Some side effects of this medication that your pet might have include gagging, drooling, and reddish-brown urine.

Reviewed by:Last reviewed on March 27, 2025
Paws

For pets

Metronidazole can be prescribed or used off-label by a licensed veterinarian for pets. Medications prescribed for pets aren't intended for human use.

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What is Metronidazole for pets?

What is Metronidazole for pets used for?

How Metronidazole for pets works

Metronidazole is a nitroimidazole antibiotic. It kills bacteria and parasites by damaging their genetic material. Metronidazole can also help lower inflammation (swelling and pain) in the gut that’s caused by the infection.

Drug facts

Common BrandsFlagyl
Drug ClassNitroimidazole antibiotic
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only
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Side effects of Metronidazole for pets

The following side effects might get better over time as your pet gets used to the medication. Let your veterinarian know immediately if your pet continues to experience these symptoms or if they worsen over time.

Common Side Effects

Less Common Side Effects

  • Not eating
  • Vomiting

Metronidazole serious side effects

Contact your veterinarian immediately if your pet experiences any of the following.

  • Serious allergic reaction: hives, fast heart rate, trouble breathing
  • Serious skin reaction (cutaneous vasculitis): scaling of the skin, bruises, bumps, purple or red spots, cuts, swelling, hair loss, fever, not eating much
  • Symptoms of too much medication: trouble walking, tremors, enlarged pupils, rapid eye movements, twitching, seizures
  • Nausea and vomiting that doesn’t get better over time

Source: Prescribing Information

The following Metronidazole side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Agitation

back pain

blindness

blurred vision

burning, numbness, tingling, or painful sensations in the hands or feet

changes in speech patterns

confusion

decreased vision

depression

dizziness

drowsiness

eye pain

fever

headache

irritability

lack of coordination

nausea

seeing or hearing things that are not there

seizures

shakiness and unsteady walk

slurred speech

stiff neck or back

trouble speaking

unsteadiness, trembling, or other problems with muscle control or coordination

unusual tiredness or weakness

vomiting

weakness in the arms, hands, legs, or feet

Less common

Black, tarry stools

blood in the urine

body aches or pain

burning while urinating

chills

clumsiness or unsteadiness

difficulty with breathing

ear congestion

fainting

feeling of pelvic pressure

frequent or painful urination

irregular heartbeat

loss of voice

nasal congestion

pinpoint red spots on the skin

runny nose

skin rash, hives, redness, itching

sneezing

stomach and back pain (severe)

unusual bleeding or bruising

vaginal irritation, discharge, or dryness not present before taking the medicine

Rare

Bleeding gums

bloating

chest pain

constipation

cough

dark urine

fast heartbeat

indigestion

loss of appetite

painful or difficult urination

pains in the stomach, side, or abdomen, possibly radiating to the back

sore throat

sores, ulcers, or white spots on the lips or in the mouth

swollen glands

yellow eyes or skin

Incidence not known

Blistering, peeling, or loosening of the skin

bloody or cloudy urine

burning while urinating

continuing diarrhea

continuing stomach pain

diarrhea

feeling of warmth

increased volume of pale, dilute urine

joint or muscle pain

loss of bladder control

red skin lesions, often with a purple center

red, irritated eyes

redness of the face, neck, arms, and occasionally, upper chest

redness of the skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Dizziness or lightheadedness

feeling of constant movement of self or surroundings

heartburn

sensation of spinning

stomach cramps

trouble sleeping

weight loss

Rare

Change in taste sensation

congestion

dry mouth

pain or tenderness around the eyes and cheekbones

tender, swollen glands in the neck

trouble with swallowing

unpleasant or sharp metallic taste

voice changes

Incidence not known

Decreased interest in sexual intercourse

inability to have or keep an erection

loss in sexual ability, desire, drive, or performance

painful sexual intercourse

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Pros and cons of Metronidazole for pets

Pros

  • Taken by mouth, so easier to give to pet at home compared to an injection
  • Pills can be made into an oral liquid by a compounding pharmacy
  • Treatment generally lasts 5 to 7 days

Cons

  • Typically given twice daily
  • Bitter taste, so can be challenging to give to pet
  • Not for dogs and cats that are pregnant or nursing
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Pharmacist tips for Metronidazole for pets

pharmacist
  • It’s important to give your pet the full course of the antibiotic treatment with metronidazole as directed by their veterinarian. Stopping treatment early can cause their infection to come back and become more difficult to treat.
  • Metronidazole tablets have a bitter taste that your pet might not like. Ask your veterinarian about ways to give this antibiotic to your dog or cat. They might recommend that you hide it in pill pockets, which are treats for pets with a place to put the medication in the middle. Or, ask your veterinarian if it’s appropriate to hide it in any other snacks that your pet likes.
  • If your pet is having a hard time taking the pill form of metronidazole, ask your veterinarian if it’s appropriate for you to get a liquid version made at a compounding pharmacy. Sometimes, it might be easier to give a pet the liquid version than the pill form.
  • Metronidazole can cause your pet’s urine to turn a reddish-brown color. This is an expected side effect and isn’t harmful to your pet. This side effect will go away after your pet finishes their course of metronidazole.
  • If your pet continues to have diarrhea after taking metronidazole, let your veterinarian know. While metronidazole is helpful for treating diarrhea caused by certain parasites, it’s not appropriate for all cases of diarrhea. If this medication isn’t working well, your veterinarian can let you know about other treatment options.
  • Wash your hands after giving metronidazole to your pet. And don’t let your pet lick you right after they take their dose. Some people might be sensitive to metronidazole and getting this medication on the skin can lead to rash.
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Common questions about Metronidazole for pets

Once you start giving your dog metronidazole, the medication will get absorbed within a few hours. But you might not notice an improvement in your dog’s symptoms, such as fewer loose stools, until a few days later. It’s important that your dog finishes the full course of metronidazole prescribed by the veterinarian, even if your dog seems to feel better before then. Stopping an antibiotic too early can cause the infection to come back and become more difficult to treat.

Your veterinarian will let you know how long to give your dog metronidazole. Typically, a treatment course lasts 5 to 7 days. But this can differ from dog to dog depending on what type of infection they have, how serious it is, and whether or not they’re experiencing serious side effects from metronidazole. Talk with your veterinarian if you have concerns about how long your dog should take this medication.

You might be able to give metronidazole to your dog without food, depending on the form of the medication. In general, metronidazole tablets and capsules are bitter, so it’s recommended that you give the pills to your dog with a tasty treat to mask the taste. But you might not have this problem if your veterinarian gives you a prescription for a compounded liquid solution. The compounding pharmacist typically adds a flavoring agent to make this liquid solution taste better for your dog. In addition, some dogs feel nauseous from taking metronidazole, so giving this medication with food can help. Ask your veterinarian about the best way to give metronidazole to your dog.

Metronidazole pills taste bitter, so your dog might not want to take them. One way to help is by hiding the pill in foods or treats. You can also buy pill pockets from local pet stores. Another tip is to place the pill at the back of your dog’s throat, gently close their mouth, and stroke their throat to help them swallow. If pills are too hard to give, ask your vet about the liquid version (Ayradia) or having it compounded into a flavored liquid. Some dogs find liquids easier to take.

Metronidazole tablets and capsules taste bitter, so your cat might not take them easily. You can try hiding the pill in a pill pocket available at pet stores. If your cat refuses pills, ask your vet if metronidazole can be made into a flavored liquid by a compounding pharmacy. Pharmacists often add flavorings to compounded pet medications to make them taste better. Also try to speak calmly to lessen the stress your cat might be feeling. Sometimes, it helps to wrap your cat in a blanket to soothe them. If needed, ask your veterinarian for suggestions about the best way to give metronidazole to your cat.

Metronidazole isn’t known to cause constipation in cats. It’s more likely to cause diarrhea as a side effect because this antibiotic affects the balance of bacteria in your cat’s gut. If your cat experiences gut-related problems after starting metronidazole, talk with your veterinarian; they can let you know if your cat needs more medical attention.

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Risks and warnings for Metronidazole for pets

Metronidazole can cause some serious health issues. This risk might be even higher for certain pets. If this worries you, talk to your veterinarian about other options.

Risk of serious neurologic effects

  • Risk factors: Taking higher doses of metronidazole | Taking metronidazole for a longer period of time | Pets who have seizures

If the dose of metronidazole is too high for your dog or cat, it can cause serious neurological side effects, including movement problems, tremors, seizures. The risk is higher for pets that already have seizure conditions or are taking seizure medications. Let your veterinarian know right away if you notice these symptoms in your pet so they can let you know about the next steps.

Possible medication interactions

Based on how metronidazole works in the body and data from human studies, there’s a risk that it can interact with certain medications, including cimetidine (Tagamet), warfarin (Coumadin), and certain seizure medications. Let your veterinarian know about all the medications your pet is taking before starting metronidazole. Your veterinarian can help you check for possible interactions with metronidazole to keep your pet safe.

Not for dogs and cats that are pregnant or nursing

Metronidazole shouldn’t be given to dogs and cats that are pregnant or nursing. Though studies are limited, there’s a risk that this medication can cause serious harm during pregnancy. Metronidazole can also pass into mother’s milk and cause harm to nursing puppies or kittens. If your cat or dog is pregnant or nursing, let your veterinarian know. They can talk with you about options for your pet.

Use with caution in animals with liver or kidney problems

Let your veterinarian know if your dog or cat has liver or kidney problems. Metronidazole is mainly processed through the liver, and cleared from the body through both the liver and kidney. If your pet’s liver or kidney isn’t working well, they’re more likely to experience side effects. In some cases, the veterinarian will consider giving your pet a lower dose of metronidazole.

Risk of serious skin condition

Though rare, pets that take metronidazole might experience a serious skin reaction called cutaneous vasculitis. This condition is caused by inflammation of the blood vessels. Get medical help right away if you notice symptoms of this skin reaction in your pet, such as cuts and bruises on the skin, purple or red spots on the skin, and fever. They might need more medical attention.

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Metronidazole dosage forms for pets

The average cost for 14 tablets of 500mg of Metronidazole is $8.62 with a free GoodRx coupon. This is 62.62% off the average retail price of $23.06.
bottle of lotionBottle of lotion
DosageQuantityPrice as low asPrice per unit
59ml of 0.75%1 bottle$55.54$55.54
capsuleCapsule
DosageQuantityPrice as low asPrice per unit
375mg14 capsules$55.32$3.95
gel pumpGel pump
DosageQuantityPrice as low asPrice per unit
55g of 1%1 pump$38.28$38.28
packagePackage
DosageQuantityPrice as low asPrice per unit
70g of 0.75% gel1 package$22.53$22.53
tabletTablet
DosageQuantityPrice as low asPrice per unit
250mg30 tablets$6.67$0.22
500mg14 tablets$8.62$0.62
125mg14 tablets$192.05$13.72
tube of creamTube of cream
DosageQuantityPrice as low asPrice per unit
45g of 0.75%1 tube$22.71$22.71
tube of gelTube of gel
DosageQuantityPrice as low asPrice per unit
45g of 0.75%1 tube$24.56$24.56
60g of 1%1 tube$41.21$41.21

Typical dosage for Metronidazole

Your veterinarian generally determines the dose of metronidazole for your cat or dog based on their body weight. But the dose can differ depending on other factors, such as your pet’s health condition or the type of infection the veterinarian thinks your pet has.

An example of possible dosing:

  • Dogs and cats: The typical dose is 15 mg/kg by mouth every 12 hours.
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Interactions between Metronidazole and other drugs for pets

Metronidazole might interact with certain medications or supplements. Always let your veterinarian know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that your pet is currently taking. The list below does not include all possible drug interactions with Metronidazole. Please note that only the generic name of each medication is listed below.

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

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Metronidazole images

White Oblong K And 11 - Metronidazole 500mg Tablet
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References

Best studies we found

American College of Veterinary Ophthalmologists. (2020). How to give medicine to your pet by mouth.

American College of Veterinary Pharmacists. (n.d.). Metronidazole.

American Veterinary Medical Association. (n.d.). Compounding FAQ for pet owners.

GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.

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