Nitroimidazole antibiotics are used to treat bacterial infections, certain parasitic infections, and some types of vaginal infections. They also have other uses, such as treating infections of the skin, gastrointestinal tract, and in some cases, joint infections. These medications work by disrupting the DNA of the bacteria or parasites, which stops them from growing and multiplying. Nitroimidazole antibiotics come in different forms, including oral pills, topical creams, and gels. Examples include metronidazole (Flagyl, Metrogel, Metrocream, Metrolotion) and tinidazole (Tindamax). You can choose the form that best fits your needs.