Head-to-head comparisons of medication uses, side effects, warnings, and more.
Quinine (Qualaquin)
Doxycycline hyclate
Quinine (Qualaquin)
Doxycycline hyclate
Summary of Qualaquin vs. Vibramycin
Summary for Antimalarial
Prescription only
Quinine (Qualaquin) is used to treat malaria in people ages 16 years and older. It's not used for preventing malaria. It's available as a capsule taken every 8 hours. Side effects of quinine (Qualaquin) include nausea, stomach pain, and vomiting. Taking it with food can ease some stomach-related side effects. It's typically not a first-choice option because it has a lot of side effects, drug interactions, and needs to be taken in combination with either doxycycline (Vibramycin, Doryx) or certain other antimalarial medications.
•Treatment of uncomplicated malaria caused by Plasmodium falciparum in people ages 16 years and older
Indications for
Doxycycline hyclate is used to prevent malaria due to the parasite Plasmodium falciparum and to treat many different infections caused by bacteria. Some examples include:
•Respiratory tract infections, including in the nose, throat, and lungs
•Infections caused by ticks, mites, or fleas (Rocky Mountain spotted fever or typhus fever)
•Sexually-transmitted infections (STIs) like chlamydia, gonorrhea, chancroid, and syphilis
•Lyme disease
•Urinary tract infections (UTIs)
•Severe acne
•Anthrax
•Plague
•Cholera
Pros and Cons of Qualaquin vs. Vibramycin
Pros and Const for Antimalarial
Pros
•Only need to take for a week to treat malaria
•Taken by mouth
•Available as a lower-cost generic
Cons
•Taken every 8 hours
•Only available as a capsule
•Interacts with a lot of medications, including certain antiseizure medications and antibiotics
Pros and Const for Tetracycline antibiotic
Pros
•Good alternative for some infections if you're allergic to penicillins