liraglutide
Victoza (liraglutide) is a medication that's injected once a day. It helps lower blood sugar levels in people 10 years and older with Type 2 diabetes when used with a nutritious diet and regular exercise. It can also help lower the risk of heart-related problems in adults with Type 2 diabetes and heart disease. Victoza (liraglutide) belongs to the drug class called GLP-1 agonists. The medication comes as single-dose prefilled pens and is injected under the skin. It can cause side effects like nausea, vomiting, diarrhea, and constipation. Victoza (liraglutide) is available as both a brand-name and generic medication.
What is Victoza (liraglutide)?
What is Victoza (liraglutide) used for?
- Type 2 diabetes in people age 10 and older, together with a balanced diet and exercise
- Lowering the risk of serious heart-related problems in adults with Type 2 diabetes and heart disease
How Victoza (liraglutide) works
Victoza (liraglutide) is a glucagon-like peptide-1 receptor agonist, or GLP-1 agonist for short. It works in a similar way to GLP-1, which is a hormone your body naturally makes.
Victoza (liraglutide) tells your body to release more insulin from the pancreas. Insulin helps move glucose (sugar) from the blood and into your cells for energy. The medication also keeps the stored form of sugar in the body from getting into the blood. These actions help lower your blood sugar levels.
Drug facts
Side effects of Victoza (liraglutide)
The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Nausea (up to 20%)
- Diarrhea (up to 12%)
- Headache (up to 11%)
- Common cold symptoms (up to 10%)
- Lower appetite (up to 10%)
- Vomiting (up to 9%)
- Indigestion (up to 7%)
- Upper respiratory tract infection (up to 7%)
- Constipation (5%)
Less Common Side Effects
- Dizziness
- Back pain
- Injection site reaction (e.g., rash, redness)
Victoza (liraglutide) serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Allergic reaction: hives, trouble breathing, swelling of the face or throat
- Pancreatitis or gallstones: severe stomach or back pain, vomiting, yellowing of the skin or eyes
More on Victoza (liraglutide) side effects
The following Victoza (liraglutide) side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
Bladder pain
bloody or cloudy urine
chills
difficult, burning, or painful urination
frequent urge to urinate
general feeling of discomfort or illness
headache
hoarseness
joint pain
loss of appetite
lower back or side pain
muscle aches and pains
shivering
sweating
trouble sleeping
unusual tiredness or weakness
vomiting
Less common
Blurred vision
dizziness
nervousness
pounding in the ears
slow or fast heartbeat
Rare
cold sweats
confusion
cool, pale skin
hives or welts, itching, or skin rash
increased hunger
large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals
loss of consciousness
nightmares
redness of the skin
seizures
shakiness
slurred speech
Incidence not known
Agitation
clay-colored stools
confusion
dark urine
decreased awareness or responsiveness
decreased urine output
difficulty with swallowing
hostility
irritability
muscle twitching
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
rapid weight gain
severe sleepiness
swelling of the face, ankles, or hands
tightness in the chest
unpleasant breath odor
vomiting of blood
yellow eyes or skin
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Get your GoodRx coupon
Pros and cons of Victoza (liraglutide)
Pros
Cons
- Must inject once a day
- Might have uncomfortable side effects, like nausea, diarrhea, and headache
- Can slow down gut movement, which can affect how other medications get absorbed into the body
Pharmacist tips for Victoza (liraglutide)
- Inject Victoza (liraglutide) once every day. Pick a time that works best for you. It doesn't matter if you inject close to a meal or not.
- Try to inject Victoza (liraglutide) at the same time every day. This can help make it part of your daily routine. You can also set up reminders on your phone to help yourself remember when to take the medication.
- Most people start to see changes in their blood sugar about 2 weeks after starting Victoza (liraglutide). You probably won't see changes with the starting dose of 0.6 mg. This low dose helps your body get used to the medication and lowers the chance of side effects like nausea.
- You'll need to buy needles separately for your Victoza (liraglutide) injections. This medication doesn't come with needles. Ask your prescriber or pharmacist about the right needles for your pen.
- Don't reuse old needles if you're running low for your Victoza (liraglutide) pens. Use a new needle with each injection to prevent germs from spreading and infection. Ask your prescriber or pharmacist for needles if you're out.
- If you miss a dose of Victoza (liraglutide), skip it and wait to inject your usual dose of medication the next day. Don't double up on your dose to make up for the one you missed because this can raise your risk of side effects. If you forget to take Victoza (liraglutide) for 3 days in a row, talk to your prescriber. You'll have to restart the medication at a lower dose.
Tips on how to use the Victoza (liraglutide) pen:
- Your healthcare team will show you how to use and inject Victoza (liraglutide). They'll make sure you can do it on your own first. Read the Instructions for Use, and ask your prescriber or pharmacist if you have any questions.
- Don't share Victoza (liraglutide) pens, even if you put a new needle on it. Sharing pens can be harmful because it can spread infections to others.
- How to store Victoza (liraglutide): Store unused pens in the refrigerator, but don't freeze them. After you use a pen for the first time, you can keep it either at room temperature (up to 86ºF) or in the fridge for 30 days. Throw it away after this time. Store the pen without a needle on it when you're not using it.
- Prime each new Victoza (liraglutide) pen before using: Follow the directions in the "First Time Use for Each New Pen" section of the instructions to prime a new pen. You only need to prime it once. This makes sure the pen is ready for you to use and will give you a full dose of medication each time you use it.
- Where to inject Victoza (liraglutide): Inject the medication under the skin of your stomach or thigh. Someone can also help you inject it into the fatty area in the back of your upper arm. Choose a different spot within the same area for each injection. This helps prevent skin irritation or damage.
- How to inject Victoza (liraglutide): Turn the dose selector to your prescribed dose. After inserting the needle into the skin, press down on the dose button until "0 mg" lines up with the pointer. Keep the dose button pressed down and count to 6 to make sure you get all the medication for your dose. Then, lift up the pen. Carefully cover the needle with the needle cap and unscrew it from the pen.
- How to throw away Victoza (liraglutide): Throw away used needles and empty pens in a sharps container. Also place your pen in this container after it's been 30 days since you first used it. Don't throw away used needles and pens in the trash. This helps keep you and others safe from needle sticks.
More on Victoza (liraglutide) tips
Common questions about Victoza (liraglutide)
No. Victoza (liraglutide) isn't a type of insulin. But the way the medication works affects the amount of insulin in your body. Victoza (liraglutide) is a GLP-1 agonist. It acts like GLP-1, a hormone your body naturally makes that help regulate blood sugar. Victoza (liraglutide) tells your pancreas to release insulin when your blood sugar gets high. This insulin helps move sugar out of the blood and into your cells after you eat. This helps keep your blood sugar under control.
No. Victoza (liraglutide) and Ozempic (semaglutide) are different injectable GLP-1 medications for Type 2 diabetes. The main difference is how often you take them. Victoza is injected under the skin once every day. But Ozempic is injected under the skin just once a week. Studies show that Ozempic might lower A1C (your average blood sugar level over time) more than Victoza after about 7 months. Talk to your prescriber to learn more about the differences between them.
Studies suggest that Victoza (liraglutide) can help adults with Type 2 diabetes lose weight. This might be because the medication can lower appetite. In a study, people with Type 2 diabetes taking 1.2 mg of Victoza (liraglutide) lost an average of 4.6 pounds in a year. Those taking 1.8 mg of the medication lost an average of 5.5 pounds in the same time. Weight loss might be an added benefit for people with Type 2 diabetes taking this medication. But Victoza (liraglutide) isn't FDA approved for weight loss. So using it for weight loss is "off-label." A higher-dose version of liraglutide called Saxenda is approved specifically for that. Talk to your prescriber if you want help with managing your weight.
Common side effects of Victoza (liraglutide), like nausea, vomiting, and diarrhea, usually don't last very long for most people. They often go away over time. Redness, soreness, or swelling where you gave the injection should go away on their own after a couple days. Talk to your care team if any side effects bother you, get worse, or don't go away.
Store unused Victoza (liraglutide) pens in the refrigerator. But make sure they don't freeze. Once you start using a pen, you can keep it at room temperature (up to 86ºF) or in the fridge for up to 30 days.
There's no set time for how long you can use Victoza (liraglutide). Most people keep using it as long as side effects aren't bothering them too much. They'll also probably keep using the medication if it helps with their blood sugar or A1C levels. Talk to your prescriber about how Victoza (liraglutide) is working for you and how long you might need to take it.
The FDA approved a generic version of Victoza (liraglutide) in 2024. Talk to your prescriber or pharmacist about if it's possible to switch from brand name to generic. It might also depend on which version your insurance plan prefers.
Inject Victoza (liraglutide) into the fatty tissue under the skin. The best places to inject it into are the stomach, thigh, or upper arm (with someone's help). Be sure to choose a different spot to inject into each time so that you don't irritate your skin. Don't inject the medication into a vein or muscle. Ask your prescriber or pharmacist if you're not sure where to inject Victoza (liraglutide).
How to save using GoodRx
Risks and warnings for Victoza (liraglutide)
Victoza (liraglutide) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Possible risk of thyroid cancer
In animal studies, some rats and mice got thyroid cancer when they were given Victoza (liraglutide). It was more likely to happen when these animals got higher doses or were given the medication for a long time. It's not known if Victoza (liraglutide) can cause thyroid cancer in people.
Because of this risk, people with a type of thyroid cancer called medullary thyroid cancer (MTC) can't take Victoza (liraglutide). People with a family member who had this cancer also can't take Victoza (liraglutide). In addition, those with multiple endocrine neoplasia syndrome type 2 (MEN 2) can't take this medication.
Talk to your prescriber if you're worried about the risk of thyroid cancer. Call your care team right away if you feel a lump in your neck or throat. Also let them know if you have trouble breathing, trouble swallowing, or a hoarse voice that won't go away. These could be signs of thyroid cancer.
Inflammation of the pancreas (pancreatitis)
- Risk factors: History of gallstones | History of alcohol use disorder
Although it's rare, some people who used Victoza (liraglutide) had swelling in their pancreas (called pancreatitis). Sometimes, it can be serious. It's not clear if people who've had pancreatitis before are more likely to get it again while using this medication.
Stop taking Victoza (liraglutide) and tell your prescriber right away if you have signs of pancreatitis. Watch for severe stomach or back pain. Also be aware of any stomach problems that make you vomit.
Low blood sugar (hypoglycemia)
- Risk factors: Also using insulin | Also taking a sulfonylurea (like glipizide) | Children
Victoza (liraglutide) lowers your blood sugar levels. But sometimes, it can drop too low, which can be dangerous. This is more likely if you also use insulin or take a sulfonylurea like glipizide. Tell your prescriber about any other diabetes medications you take. They can see if you need any dose changes to keep you safe.
Make sure you and your loved ones know how to spot low blood sugar. Signs include feeling very hungry, shaky, dizzy, weak, or confused. You might also have a fast heartbeat or sweat a lot. Treat low blood sugar with fast-acting carbohydrates, like glucose tablets or hard candy. Call your prescriber if you have low blood sugar while you're taking Victoza (liraglutide).
Kidney damage
- Risk factors: Kidney problems | Taking other medications that can harm the kidneys | Low fluids in the body (dehydration)
Some people who took Victoza (liraglutide) had kidney problems. This included people with and without kidney problems to begin with. In some cases, they needed dialysis. Most people got better after stopping Victoza (liraglutide) or after getting treated for the kidney problem. Tell your prescriber if you have kidney problems so they can make sure the medication is safe for you.
Drink plenty of fluids to stay hydrated. Let your care team know if you have a lot of nausea, vomiting, or diarrhea while taking Victoza (liraglutide). This can make you dehydrated, which can sometimes hurt your kidneys. Also tell them if you can't urinate or are urinating less than usual. This could be a sign of a kidney problem.
Allergic reactions
- Risk factors: Previous allergic reaction to another GLP-1 agonist
Some people have had serious allergic reactions to Victoza (liraglutide). Signs include rash; trouble breathing; or swelling of the face, lips, tongue, or throat. There also could be other signs of anaphylaxis. Call 911 or go to the emergency room right away if this happens while using Victoza (liraglutide).
Tell your prescriber if you've have an allergic reaction to other GLP-1 medications before. It's not clear if that raises your risk with Victoza (liraglutide). Don't take Victoza (liraglutide) if you've had an allergic reaction to Saxenda since it has the same active ingredient.
Gallbladder problems
It's rare, but some people who took Victoza (liraglutide) had gallbladder problems like gallstones. Call your care team right away if you have sudden severe pain in the upper stomach or back, fever, or yellow skin or eyes. These can be signs of gallbladder problems. Your prescriber will probably run tests to check if your gallbladder is okay.
Lung problems during general anesthesia or deep sedation
While under general anesthesia or deep sleep, some people taking GLP-1 medications like Victoza (liraglutide) had a serious lung problem. This happened when food or liquid got into the lungs.
It's rare, but this lung problem can happen because Victoza (liraglutide) slows down your gut. So even if you followed instructions not to eat before your procedure, food might stay in your stomach and get into the lungs.
Before any surgery or medical procedure, tell the care team that you're taking Victoza (liraglutide). Your care team can watch for this lung problem and help keep you safe during the procedure.
Victoza (liraglutide) dosage
Carton| Dosage | Quantity | Price as low as | Price per unit |
|---|---|---|---|
| 2 pens of 18mg/3ml | 1 carton | $161.98 | $161.98 |
| 3 pens of 18mg/3ml | 1 carton | $228.57 | $228.57 |
Typical dosage for Victoza (liraglutide)
This medication is injected under the skin on the stomach, thigh, or back of the upper arm.
The typical starting dose is 0.6 mg injected once daily.
After at least 1 week, your prescriber might raise the dose to 1.2 mg injected once daily.
After at least another week, your prescriber can raise the dose again to 1.8 mg injected once daily, if needed. This is the highest dose you can take.
More on Victoza (liraglutide) dosage
Interactions between Victoza (liraglutide) and other drugs
More on Victoza (liraglutide) interactions
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Balofloxacin
- Besifloxacin
- Chloroquine
- Ciprofloxacin
- Enoxacin
- Fleroxacin
- Flumequine
- Gatifloxacin
- Gemifloxacin
- Hydroxychloroquine
- Insulin
- Insulin Aspart, Recombinant
- Insulin Bovine
- Insulin Degludec
- Insulin Detemir
- Insulin Glargine, Recombinant
- Insulin Glulisine
- Insulin Lispro, Recombinant
- Lanreotide
- Levofloxacin
- Lomefloxacin
- Moxifloxacin
- Nadifloxacin
- Norfloxacin
- Octreotide
- Ofloxacin
- Pasireotide
- Pazufloxacin
- Pefloxacin
- Prulifloxacin
- Rufloxacin
- Sparfloxacin
- Thioctic Acid
- Tosufloxacin
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Acebutolol
- Atenolol
- Betaxolol
- Bisoprolol
- Carteolol
- Carvedilol
- Celiprolol
- Esmolol
- Labetalol
- Levobunolol
- Metipranolol
- Metoprolol
- Nadolol
- Nebivolol
- Oxprenolol
- Penbutolol
- Pindolol
- Practolol
- Propranolol
- Sotalol
- Timolol
How much does Victoza (liraglutide) cost?
Victoza (liraglutide) contraindications
Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Victoza (liraglutide) will not be safe for you to take.
- Personal or family history of medullary thyroid carcinoma (MTC)
- Multiple endocrine neoplasia syndrome type 2 (MEN 2)
- Allergic reaction to other liraglutide products (Saxenda)
What are alternatives to Victoza (liraglutide)?
News about Victoza (liraglutide)
Victoza (liraglutide) images
