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Losartan / HCTZ Coupon - Losartan / HCTZ 100mg/25mg tablet

losartan / HCTZ

Generic Hyzaar
Used for Hypertension
Used for Hypertension

Hyzaar (losartan / hydrochlorothiazide) is a combination medication that contains two first-choice options for lowering blood pressure. This medication is taken by mouth once daily. Like other blood pressure medications, Hyzaar (losartan / hydrochlorothiazide) can cause you to feel dizzy, especially when you first start this medication or when your provider raises your dose.

Reviewed by:
reviewer
Robert Chad Hakim, PharmD, BCCCP
reviewer
Kristianne Hannemann, PharmD
Last reviewed on February 20, 2023
BasicsSide effectsPros & consPharmacist tipsFAQsWarningsDosageInteractionsCostContraindicationsAlternativesLatest newsImagesReferencesPricesMedicare
basics-icon

What is Hyzaar (losartan / hydrochlorothiazide)?

What is Hyzaar (losartan / hydrochlorothiazide) used for?

How Hyzaar (losartan / hydrochlorothiazide) works

Hyzaar (losartan / hydrochlorothiazide) is a combination of two medications that work together to lower blood pressure:

  • Losartan is an angiotensin II receptor blocker (ARB). It works by blocking angiotensin II, a hormone that raises your blood pressure, from attaching to its receptors (signaling proteins). In doing so, losartan lowers your blood pressure by relaxing the blood vessels.

  • Hydrochlorothiazide is a thiazide diuretic (water pill). It works in your kidneys to remove extra water and certain electrolytes (like sodium and potassium). This helps lower blood pressure.

Are you looking for information on losartan (Cozaar) or hydrochlorothiazide instead?
When does Hyzaar (losartan / hydrochlorothiazide) start working?
Time passed since treatment started:
HOURS
DAYS
WEEKS
MONTHS
Initial effect
Full effect

Drug Facts

Common BrandsHyzaar
Drug ClassARB / Diuretic (water pill) combo
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only
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$48.470
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What are the side effects of Hyzaar (losartan / hydrochlorothiazide)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Upper respiratory tract infection (i.e., common cold; 6%)
  • Dizziness (6%)
  • Back pain (2%)

Other Side Effects

  • Headache
  • Trouble sleeping
  • Rash
  • Stomach upset

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Dangerously low blood pressure: dizziness, lightheadedness, pale skin, feeling faint
  • Serious kidney problems: urinating less often than usual, swelling in your feet, ankles, or hands, unexplained weight gain
  • High blood potassium levels: nausea, muscle weakness, abnormal heartbeat
  • Severe allergic reaction: swelling of your lips, tongue, throat, or face, trouble breathing, rash
When do Hyzaar (losartan / hydrochlorothiazide) possible side effects begin and end?
Time passed since treatment started:
HOURS
DAYS
WEEKS
MONTHS
Dizziness
Headache

Source: Daily

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Rare

Black, tarry stools

blood in the urine or stools

cough or hoarseness accompanied by chills or fever, lower back or side pain, or painful or difficult urination

fainting

pinpoint red spots on the skin

pounding heartbeat

severe stomach pain, nausea, and vomiting

skin rash

swelling of the feet or lower legs

unusual bleeding or bruising

Incidence not known

Bleeding gums

blistering, peeling, loosening of the skin

blurred vision

chest pain or tightness

chills

coma

confusion

cough

dark-colored urine

decreased frequency of urine

decreased urine output

diarrhea

difficulty swallowing

dizziness

dry mouth

fast, irregular, pounding, or racing heartbeat or pulse

fever

hives, itching skin, rash

increased sensitivity of the skin to sunlight

increased thirst

irritability

joint or muscle pain

large, flat, blue, or purplish patches in the skin

large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

light-colored stools

loss of appetite

lower back or side pain

muscle cramps, pain, spasms, stiffness, or twitching

nausea or vomiting

numbness or tingling in the hands, feet, or lips

painful knees and ankles

persistent non-healing sore

pink growth

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

raised red swellings on the skin, the buttocks, legs, or ankles

red, irritated eyes

red skin lesions, often with a purple center

reddish patch or irritated area

redness or other discoloration of the skin

restlessness

seizures

severe sunburn

shiny bump

sore throat

sores, ulcers, or white spots in the mouth or on the lips

swelling of the face, ankles, or hands

trouble breathing

upper right abdominal or stomach pain

unusual tiredness or weakness

weak or irregular heartbeat

weight gain

white, yellow or waxy scar-like area

yellow eyes and skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Body aches or pain

headache

loss of voice

sneezing

sore throat

stuffy or runny nose

Rare

Dry cough

Incidence not known

Acid or sour stomach

belching

change or loss of taste

difficulty having a bowel movement (stool)

general feeling of discomfort or illness

heartburn

inability to have or keep an erection

indigestion

loss in sexual ability, desire, drive, or performance

trouble sleeping

weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Hyzaar (losartan / hydrochlorothiazide)

thumbs-up

Pros

Contains two first-choice blood pressure medications

Convenient to take a combination of two medications in one pill taken just once a day

Protects your kidneys, which is especially useful for people with diabetes or mild-to-moderate kidney disease

Taken by mouth once per day

thumbs-down

Cons

Can make you urinate more often

Must be avoided in pregnant females

More difficult to customize the dose since Hyzaar (losartan / hydrochlorothiazide) is a combination of two medications

Only available as a tablet

pharmacist-tips

Pharmacist tips for Hyzaar (losartan / hydrochlorothiazide)

pharmacist

  • Take Hyzaar (losartan / hydrochlorothiazide) with or without food at any time of day. If it hurts your stomach, try taking it with food to help.

    • You might feel dizzy when you start taking Hyzaar (losartan / hydrochlorothiazide), and when the dose is raised. This should get better over time as you continue taking the medication and your body gets used to your new blood pressure. Stand up slowly and carefully from a sitting or lying down position to avoid falling.

      • If you feel dizzy, lightheaded, feeling like you're going to faint, tired, or confused while taking Hyzaar (losartan / hydrochlorothiazide), your blood pressure might be too low. Make sure to hold onto something when standing and slowly sit or lie down if you can. Call your provider if this happens because your dose might need to be changed.

        • Make sure to mark your calendar with your appointments to see your provider and to get any blood work done when you take Hyzaar (losartan / hydrochlorothiazide). Your provider may order tests (e.g., potassium level, kidney function, blood pressure) during treatment and might change your dose of Hyzaar (losartan / hydrochlorothiazide) based on your lab results.

          • Take Hyzaar (losartan / hydrochlorothiazide) exactly as prescribed. Don't change your dose or suddenly stop taking the medication without talking to your provider first. Doing so can cause your blood pressure to rise quickly. If you want to stop Hyzaar (losartan / hydrochlorothiazide), ask your provider if it's safe to do so. You might need to lower your dose slowly over time before you can completely stop taking it.

            • Hyzaar (losartan / hydrochlorothiazide) can raise your potassium levels, which can be serious. Ask your provider if you need to limit eating foods that are high in potassium. Contact your provider if you experience nausea, vomiting, or muscle weakness because these might be signs of high potassium levels.

              • Make sure to have a healthy diet, including a low-salt diet, while taking Hyzaar (losartan / hydrochlorothiazide) to help lower your blood pressure. Depending on your risk factors and other medical problems, it's possible you might be able to stop taking Hyzaar (losartan / hydrochlorothiazide) if your blood pressure gets within goal.

                • If you accidentally miss a dose of Hyzaar (losartan / hydrochlorothiazide), take it as soon as you remember. But if it's close to your next dose, then skip that dose and take your next dose at your regularly scheduled time. Don't take 2 doses of Hyzaar (losartan / hydrochlorothiazide) at the same time to make up for any missed doses, because this could lead to dangerous side effects.

                  faqs

                  Frequently asked questions about Hyzaar (losartan / hydrochlorothiazide)

                  How well does Hyzaar (losartan / hydrochlorothiazide) work?
                  The two medications that make up Hyzaar (losartan / hydrochlorothiazide) are both first-choice medication options for treating high blood pressure. In clinical studies of people with high blood pressure, Hyzaar (losartan / hydrochlorothiazide) worked better at lowering blood pressure than either losartan or hydrochlorothiazide alone. Keep in mind that though you can't directly feel the effects of blood pressure medications, controlling your blood pressure with Hyzaar (losartan / hydrochlorothiazide) helps to prevent severe and life-threatening heart problems that can come from high blood pressure, such as heart attack, stroke, and heart failure.
                  Can I start Hyzaar (losartan / hydrochlorothiazide) right away after being diagnosed with high blood pressure?
                  Typically, providers prescribe Hyzaar (losartan / hydrochlorothiazide) for people who've already been taking either losartan (Cozaar), hydrochlorothiazide, or another blood pressure medication. But they might consider switching a person to Hyzaar (losartan / hydrochlorothiazide) if their blood pressure isn't well-controlled by a single blood pressure medication. Or providers might prescribe Hyzaar (losartan / hydrochlorothiazide) for people who have been taking and are responding well to losartan (Cozaar) and hydrochlorothiazide, but want a combination medication for convenience. Hyzaar (losartan / hydrochlorothiazide) isn't typically recommended for people who are newly diagnosed with high blood pressure. But if your blood pressure is severely high and you haven't taken a blood pressure medication before, your provider might consider Hyzaar (losartan / hydrochlorothiazide) for you.
                  When's the best time to take Hyzaar (losartan / hydrochlorothiazide)?
                  In general, it's not completely clear when the best time of day to take blood pressure medications is. Some studies show taking them at night can control blood pressure better, which results in a lower risk of severe heart problems. But, this effect hasn't been consistent with other studies. Hyzaar (losartan / hydrochlorothiazide) contains hydrochlorothiazide, which can make you urinate to get rid of extra fluid and lower your blood pressure. Some people prefer to take Hyzaar (losartan / hydrochlorothiazide) in the morning rather than at night so they can avoid waking up several times throughout the night to go to the bathroom. You should take Hyzaar (losartan / hydrochlorothiazide) at the same time every day so the levels of medication in your body stay consistent.
                  Can I take Hyzaar (losartan / hydrochlorothiazide) if I have a sulfa allergy?
                  Let your provider know if you're allergic to sulfa-containing medications. The hydrochlorothiazide in Hyzaar contains sulfonamide, a sulfa medication. However, not all sulfa medications trigger the same allergic reaction. If you had a reaction to sulfa-containing antibiotics, such as sulfamethoxazole/trimethoprim (Bactrim), it's unlikely that you'll be allergic to Hyzaar (losartan / hydrochlorothiazide). However, it's still best to check with your provider if you can take this medication.
                  Can I take Hyzaar (losartan / hydrochlorothiazide) if I'm pregnant or breastfeeding?
                  No. Both medications in Hyzaar (losartan / hydrochlorothiazide) have risks for unborn babies. Losartan can cause severe harm to your unborn baby by interfering with their kidney development and health if taken during the second or third trimesters of pregnancy, which can be life-threatening. Hydrochlorothiazide can raise the risk of low platelets or jaundice in babies born to mothers who take it during pregnancy. Additionally, animal studies show that Hyzaar (losartan / hydrochlorothiazide) can pass into breast milk, though it's not clear how this might affect the nursing baby. If you're pregnant, thinking of getting pregnant, or breastfeeding and are taking Hyzaar (losartan / hydrochlorothiazide), contact your provider right away. Your provider will likely prescribe you a different medication that's safer during pregnancy.
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                  What are the risks and warnings for Hyzaar (losartan / hydrochlorothiazide)?

                  Hyzaar (losartan / hydrochlorothiazide) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

                  risk-warning

                  Not for use during pregnancy

                  Hyzaar (losartan / hydrochlorothiazide) shouldn't be taken by pregnant females because it can cause severe harm and even death to unborn babies. If you find out that you're pregnant while taking Hyzaar (losartan / hydrochlorothiazide), stop and let your provider know right away. If you're pregnant before starting Hyzaar (losartan / hydrochlorothiazide) or thinking of becoming pregnant during treatment, discuss with your provider about safer options to treat your blood pressure.

                  risk-warning

                  Low blood pressure

                  • Risk factors: Not enough fluid in your body | Having diarrhea or vomiting for a long time | Low salt levels in your body | Taking higher doses of diuretic medications

                    Hyzaar (losartan / hydrochlorothiazide) can cause your blood pressure to drop too much, which can make you feel dizzy, tired, or lightheaded. This side effect is more common when you first start Hyzaar (losartan / hydrochlorothiazide) or when the dose is raised. Make sure to stay well-hydrated. If your blood pressure drops too much and you feel dizzy, make sure to sit down slowly while holding onto something and let your provider know. If you fall and hit your head, get medical help right away. If you feel dizzy, lightheaded, faint, tired, or confused while taking Hyzaar (losartan / hydrochlorothiazide), contact your provider right away.

                    risk-warning

                    Kidney damage

                    • Risk factors: Severe heart failure | Kidney problems | Not enough fluid in your body | Taking other medications that can cause kidney damage | History of narrow heart valves (aortic stenosis)

                      Sometimes, Hyzaar (losartan / hydrochlorothiazide) can affect your kidneys and cause them to not work as well. The risk is higher for people who have certain types of kidney problems, such as renal artery stenosis or very severe heart failure. Your provider might order lab tests every so often to make sure your kidneys are healthy and working properly. If you develop kidney problems, or if your kidney problems worsen while taking Hyzaar (losartan / hydrochlorothiazide), your provider might recommend that you stop taking this medication. Let your provider know if you're urinating less often than usual, as this could be a sign that your kidneys aren't working as well.

                      risk-warning

                      Changes in electrolyte, blood sugar, and cholesterol levels

                      Hyzaar (losartan / hydrochlorothiazide) can affect the level of certain electrolytes in your body, including sodium, potassium, and magnesium. Your provider might order bloodwork regularly while you're taking this medication to make sure your electrolyte levels are in a safe range. Let your provider know if you experience a fast heart beat, weakness, low energy, muscle pain or cramps, less urination than usual, nausea, or vomiting. These can be signs of electrolyte changes in your body.

                      In addition, hydrochlorothiazide can change the way your body responds to blood sugar. It can also raise your cholesterol levels. Your provider might also check your blood sugar and cholesterol levels regularly while you're taking this medication.

                      risk-warning

                      Vision problems

                      • Risk factors: Sulfa or penicillin allergies

                        Though rare, some people experience vision changes within hours or weeks after starting Hyzaar (losartan / hydrochlorothiazide) because of the hydrochlorothiazide part of the medication. Tell your provider right away about any vision changes or eye pain and stop taking Hyzaar (losartan / hydrochlorothiazide) as soon as possible. In some cases, surgery might be required to avoid permanent vision loss.

                        risk-warning

                        Lupus

                        Rarely, Hyzaar (losartan / hydrochlorothiazide) can cause worsening of or new lupus. Let your provider know if you notice a rash across your cheeks and nose or feel very tired.

                        dosage

                        Hyzaar (losartan / hydrochlorothiazide) dosage forms

                        The average cost for 30 tablets of 100mg/25mg of Hyzaar (losartan / hydrochlorothiazide) is $201.87 with a free GoodRx coupon. This is 19.58% off the average retail price of $251.01.
                        tablet
                        Tablet
                        DosageQuantityPrice as low asPrice per unit
                        50mg/12.5mg30 tablets$149.12$4.97
                        100mg/12.5mg30 tablets$186.83$6.23
                        100mg/25mg30 tablets$201.87$6.73

                        Typical dosing for Hyzaar (losartan / hydrochlorothiazide)

                        • The typical dose of Hyzaar ranges from 50 mg/12.5 mg (losartan/hydrochlorothiazide) to 100 mg/25 mg (losartan/hydrochlorothiazide) by mouth once daily.

                        Your provider will adjust your dose based on how well it's helping your blood pressure and if you're having side effects.

                        interactions

                        Interactions between Hyzaar (losartan / hydrochlorothiazide) and other drugs

                        Hyzaar (losartan / hydrochlorothiazide) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Hyzaar (losartan / hydrochlorothiazide). Please note that only the generic name of each medication is listed below.

                        Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

                        Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                        Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                        drug-cost

                        How much does Hyzaar (losartan / hydrochlorothiazide) cost?

                        To access savings, use a GoodRx coupon and pay just a fraction of the retail price.
                        Hyzaar (brand)
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                        contraindications-icon

                        Hyzaar (losartan / hydrochlorothiazide) contraindications

                        Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Hyzaar (losartan / hydrochlorothiazide) will not be safe for you to take.

                        • Not producing urine

                        • Taking at the same time as aliskiren (Tekturna) in people with diabetes (high blood sugar)

                        alternatives

                        What are alternatives to Hyzaar (losartan / hydrochlorothiazide)?

                        There are a number of medications that your doctor can prescribe in place of Hyzaar (losartan / hydrochlorothiazide). Compare a few possible alternatives below.
                        Hyzaar (losartan / hydrochlorothiazide)
                        Used for:
                        $48.47 Lowest GoodRx priceView Prices
                        Benicar HCT (olmesartan / hydrochlorothiazide)
                        Used for:

                        • High blood pressure

                        $17.51 Lowest GoodRx priceView Prices
                        Zestoretic (lisinopril / hydrochlorothiazide)
                        Used for:
                        $13.56 Lowest GoodRx priceView Prices
                        images

                        Hyzaar (losartan / hydrochlorothiazide) images

                        Yellow Oval 7368 And 93 - Losartan Potassium / Hydrochlorothiazide 100mg-25mg Tablet
                        This medicine is Yellow, Oval Tablet Imprinted With "93" And "7368".Yellow Oval 7368 And 93 - Losartan Potassium / Hydrochlorothiazide 100mg-25mg Tablet
                        White Round Sz 390 - Losartan Potassium / Hydrochlorothiazide 100mg-25mg Tablet
                        This medicine is White, Round Tablet Imprinted With "Sz 390".White Round Sz 390 - Losartan Potassium / Hydrochlorothiazide 100mg-25mg Tablet
                        Yellow Oval 1118 - Losartan Potassium / Hydrochlorothiazide 100mg-25mg Tablet
                        This medicine is Yellow, Oval Tablet Imprinted With "1118".Yellow Oval 1118 - Losartan Potassium / Hydrochlorothiazide 100mg-25mg Tablet
                        Yellow Oval 49 And E - Losartan Potassium / Hydrochlorothiazide 100mg-25mg Tablet
                        This medicine is Yellow, Oval Tablet Imprinted With "E" And "49".Yellow Oval 49 And E - Losartan Potassium / Hydrochlorothiazide 100mg-25mg Tablet
                        Yellow Oval 49 And E - Losartan Potassium / Hydrochlorothiazide 100mg-25mg Tablet
                        This medicine is Yellow, Oval Tablet Imprinted With "E" And "49".Yellow Oval 49 And E - Losartan Potassium / Hydrochlorothiazide 100mg-25mg Tablet
                        Yellow Oval 49 And E - Losartan Potassium / Hydrochlorothiazide 100mg-25mg Tablet
                        This medicine is Yellow, Oval Tablet Imprinted With "E" And "49".Yellow Oval 49 And E - Losartan Potassium / Hydrochlorothiazide 100mg-25mg Tablet
                        Yellow Oval 192 And U - Losartan Potassium / Hydrochlorothiazide 100mg-25mg Tablet
                        This medicine is Yellow, Oval Tablet Imprinted With "192" And "U".Yellow Oval 192 And U - Losartan Potassium / Hydrochlorothiazide 100mg-25mg Tablet
                        Yellow Oval 192 And U - Losartan Potassium / Hydrochlorothiazide 100mg-25mg Tablet
                        This medicine is Yellow, Oval Tablet Imprinted With "192" And "U".Yellow Oval 192 And U - Losartan Potassium / Hydrochlorothiazide 100mg-25mg Tablet
                        Yellow Oblong Hh And 212 - Losartan Potassium / Hydrochlorothiazide 100mg-25mg Tablet
                        This medicine is Yellow, Oblong Tablet Imprinted With "212" And "Hh".Yellow Oblong Hh And 212 - Losartan Potassium / Hydrochlorothiazide 100mg-25mg Tablet
                        Yellow Oblong Hh And 212 - Losartan Potassium / Hydrochlorothiazide 100mg-25mg Tablet
                        This medicine is Yellow, Oblong Tablet Imprinted With "212" And "Hh".Yellow Oblong Hh And 212 - Losartan Potassium / Hydrochlorothiazide 100mg-25mg Tablet
                        Yellow Oval 49 And E - Losartan Potassium / Hydrochlorothiazide 100mg-25mg Tablet
                        This medicine is Yellow, Oval Tablet Imprinted With "E" And "49".Yellow Oval 49 And E - Losartan Potassium / Hydrochlorothiazide 100mg-25mg Tablet
                        Yellow Oval C And 339 - Losartan Potassium / Hydrochlorothiazide 100mg-25mg Tablet
                        This medicine is Yellow, Oval Tablet Imprinted With "339" And "C".Yellow Oval C And 339 - Losartan Potassium / Hydrochlorothiazide 100mg-25mg Tablet
                        Yellow Oval C And 339 - Losartan Potassium / Hydrochlorothiazide 100mg-25mg Tablet
                        This medicine is Yellow, Oval Tablet Imprinted With "339" And "C".Yellow Oval C And 339 - Losartan Potassium / Hydrochlorothiazide 100mg-25mg Tablet
                        Yellow Tear L145 - Losartan Potassium / Hydrochlorothiazide 100mg-25mg Tablet
                        This medicine is Yellow, Tear Tablet Imprinted With "L145".Yellow Tear L145 - Losartan Potassium / Hydrochlorothiazide 100mg-25mg Tablet
                        Yellow Tear M43 And Lu - Losartan Potassium / Hydrochlorothiazide 100mg-25mg Tablet
                        This medicine is Yellow, Tear Tablet Imprinted With "M43" And "Lu".Yellow Tear M43 And Lu - Losartan Potassium / Hydrochlorothiazide 100mg-25mg Tablet

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                        References

                        Best studies we found

                        American Heart Association. (2020). What is left ventricular hypertrophy (LVH)?

                        Fujisaki, K., et al. (2014). Impact of combined losartan/hydrochlorothiazide on proteinuria in patients with chronic kidney disease and hypertension. Hypertension Research: Official Journal of the Japanese Society of Hypertension.

                        Hermida, R. C., et al. (2020). Bedtime hypertension treatment improves cardiovascular risk reduction: The Hygia Chronotherapy Trial. European Heart Journal.

                        View All References (4)

                        Hill, R. D., et al. (2022). Angiotensin II Receptor Blockers (ARB). StatPearls.

                        Mackenzie, I. S., et al. (2022). Cardiovascular outcomes in adults with hypertension with evening versus morning dosing of usual antihypertensives in the UK (TIME study): A prospective, randomised, open-label, blinded-endpoint clinical trial. The Lancet.

                        Macleods Pharmaceuticals Limited. (2023). LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE - losartan potassium and hydrochlorothiazide tablet, film coated [package insert]. DailyMed.

                        Whelton, P. K., et al. (2017). 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/ PCNA guideline for the prevention, detection, evaluation, and management of high blood pressure in adults: A report of the American College of Cardiology/American Heart Association Task Force on clinical practice guidelines. Hypertension.  

                        GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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