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Felbamate Coupon - Felbamate 600mg tablet

felbamate

Generic Felbatol
Used for Epilepsy, Lennox-Gastaut Syndrome
Used for Epilepsy, Lennox-Gastaut Syndrome

Felbamate (Felbatol) helps treat partial (or focal) seizures in adults with epilepsy and in children with Lennox-Gastaut syndrome (LGS). It's typically taken by mouth 3 or 4 times a day, and the dose is adjusted based on your response to the medication. Common side effects include vomiting, stomach upset, and trouble sleeping. Felbamate (Felbatol) isn't a first-choice option because it can cause very serious side effects, like liver and blood problems. This medication is available as a tablet and an oral suspension, which are both sold as brand-name and generic versions.

Last reviewed on May 10, 2023
basics-icon

What is Felbamate (Felbatol)?

What is Felbamate (Felbatol) used for?

  • Partial seizures in adults with epilepsy

  • Seizures linked to Lennox-Gastaut syndrome (LGS) in children - add-on treatment

How Felbamate (Felbatol) works

Felbamate (Felbatol) is an antiepileptic (anti-seizure) medication. It's not entirely clear how this medication works. But it's thought that felbamate (Felbatol) helps block signals in the brain that cause seizures.

Drug Facts

Common BrandsFelbatol
Drug ClassAntiepileptic
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only
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Avg retail price
$465.60(save 87.75%)
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$57.02
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What are the side effects of Felbamate (Felbatol)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

The following side effects were reported in adults taking this medication in addition to other antiepileptics.
  • Headache (37%)
  • Nausea (34%)
  • Drowsiness (19%)
  • Low appetite (19%)
  • Dizziness (18%)
  • Difficulty sleeping (18%)
  • Tiredness (17%)
  • Vomiting (17%)
  • Indigestion (12%)
  • Constipation (11%)
Side effects might be different for children or for adults taking this medication by itself.

Other Side Effects

  • Diarrhea
  • Stomach pain
  • Uncontrollable shaking
  • Difficulty walking
  • Difficulty with movement or coordination
  • Nervousness
  • Anxiety
  • Depression
  • Double or changes in vision
  • Change in how food tastes

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Low blood cell counts: getting infections more than usual, unusual bruising or bleeding (or red or purple spots on your body), feeling very tired or weak
  • Liver injury: severe nausea, vomiting, right-sided stomach pain, fatigue, low or no appetite, yellowing of the skin or eyes
  • Thoughts of hurting yourself or of suicide

Source: DailyMed

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Black, tarry stools

chest pain

chills

confusion

cough

delusions

dementia

depression

fever

loss of bladder control

painful or difficult urination

purple or red spots on the skin

shakiness in the legs, arms, hands, or feet

shortness of breath

sore throat

sores, ulcers, or white spots on the lips or in the mouth

swollen glands

trembling or shaking of the hands or feet

unusual bleeding or bruising

unusual tiredness or weakness

Less common

Agitation, aggression, or other mood or mental changes

bladder pain

bloody or cloudy urine

bone pain

burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

clumsiness or unsteadiness

frequent urge to urinate

loss of appetite

lower back or side pain

skin rash

swelling or puffiness of the face

trouble with breathing

unsteadiness, trembling, or other problems with muscle control or coordination

Rare

Continuing headache

continuing stomach pain

continuing vomiting

dark-colored urine

general feeling of tiredness or weakness

hives or itching

light-colored stools

muscle cramps

nasal congestion

nosebleeds or other unusual bruising or bleeding

pain

sensitivity of the skin to sunlight

swollen or painful glands

tightness in the chest

yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Acid or sour stomach

bad, unusual, or unpleasant (after) taste

belching

body aches or pain

change in taste

change in walking and balance

constricted, pinpoint, or small pupils (black part of the eye)

crying

depersonalization

diarrhea

difficulty having a bowel movement (stool)

difficulty with sleeping

dizziness

double vision

dysphoria

ear congestion

euphoria

headache

heartburn

hiccup

indigestion

loss of appetite

loss of voice

nausea

paranoia

quick to react or overreact emotionally

rapidly changing moods

runny nose

seeing double

sleepiness or unusual drowsiness

sleeplessness

sneezing

stomach discomfort, upset, or pain

trouble sleeping

unable to sleep

weight loss

Less common

Blemishes on the skin

blurred vision

decreased awareness or responsiveness

decreased weight

difficulty with moving

earache

hoarseness

joint pain

muscle aching or cramping

muscle pains or stiffness

pain or tenderness around the eyes and cheekbones

pimples

redness or swelling in the ear

severe sleepiness

swollen joints

tender, swollen glands in the neck

trouble with swallowing

voice changes

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Felbamate (Felbatol)

thumbs-up

Pros

Can use by itself or with other medications to control seizures in adults

Less likely to cause sedation when used alone than some other antiseizure medications

Available as a suspension if you have trouble swallowing pills

Available as a lower-cost generic

Not a controlled substance, so it doesn't have strict regulations from the government

thumbs-down

Cons

Not a first-choice antiepileptic because of risk of serious side effects; only take if other medications haven't worked well enough

Taken 3 to 4 times a day

Interacts with some other antiepileptics, so your provider might have to adjust your doses

Dose adjustment needed if you have kidney problems because of higher risk of side effects

Unknown if safe for pregnant or breastfeeding women

pharmacist-tips

Pharmacist tips for Felbamate (Felbatol)

pharmacist
  • Before starting felbamate (Felbatol), you should have a conversation with your provider about the serious side effects that this medication can cause. You and your provider should both agree that this is the best option for you because other medications weren't working well enough.

    • Take felbamate (Felbatol) with or without food. If it upsets your stomach, you can try taking it with food to help.

      • If you're taking the suspension form of felbamate (Felbatol), ask your pharmacist for a measuring device to measure out your doses. Don't use household kitchen or measuring spoons since they might not be accurate. Keep the suspension at room temperature (don't refrigerate it), and shake the bottle well before preparing each dose.

        • Felbamate (Felbatol) can cause dizziness, drowsiness, tiredness, or difficulty with movement and coordination. Be careful doing anything that requires concentration, such as riding a bike or operating machinery, until you know how this medication affects you. Let your provider know if these side effects don't go away or are too bothersome.

          • If you notice a change in your mood, thoughts, or feelings, or if your child is behaving unusually after taking felbamate (Felbatol), let your provider know. If you have thoughts of hurting yourself, call 911 or get medical help right away.

            • Don't stop taking felbamate (Felbatol) without talking to your provider first. Stopping it too suddenly can cause seizures due to withdrawal.

              faqs

              Frequently asked questions about Felbamate (Felbatol)

              Is felbamate (Felbatol) a controlled substance?
              No, felbamate (Felbatol) isn't a controlled substance, unlike some other antiepileptics. It doesn't have the potential for misuse and dependence, so it doesn't have strict regulations from the government.
              Does felbamate (Felbatol) cause weight loss?
              Weight loss is a known side effect of felbamate (Felbatol), though it usually isn't too significant. In clinical studies, about 3% of adults taking felbamate (Felbatol) alone and 7% of children with LGS who took the medication experienced weight loss. On average, their weight went down by about 5%. Note that other side effects of felbamate (Felbatol), like nausea, vomiting, and low appetite, can possibly lead to weight loss. Keep in mind that some people taking felbamate (Felbatol) also experienced weight gain. If you're concerned about your weight, speak to your provider.
              Can I take felbamate (Felbatol) with other anti-seizure medications?
              Yes, but there are certain antiepileptics that interact with felbamate (Felbatol) that might raise your risk of side effects. These medications include phenytoin (Dilantin), valproic acid (Depakene), divalproex (Depakote), carbamazepine (Tegretol), and phenobarbital. If you're taking any of these medications, your provider will need to adjust your dose(s) when you start felbamate (Felbatol) and if you switch to a higher dose of felbamate (Felbatol). Make sure to review the dosing changes carefully with your provider and pharmacist.
              Do felbamate (Felbatol) and Lamictal work well together?
              There isn't enough information to know how well felbamate (Felbatol) and lamotrigine (Lamictal) work together to treat seizures. But, both medications have been shown to work well when used alone. While lamotrigine (Lamictal) is a first-choice treatment option for adults with newly-diagnosed partial seizures, felbamate (Felbatol) is not. And both can treat seizures due to Lennox-Gastaut syndrome. In addition, felbamate (Felbatol) and lamotrigine (Lamictal) don't appear to have any interactions with each other. Speak with your provider about felbamate (Felbatol) and lamotrigine (Lamictal). They can help you compare the two medications and guide you to the best treatment options.
              Can felbamate (Felbatol) be crushed?
              It's not known if you can crush the felbamate (Felbatol) tablet. But many manufacturers of felbamate (Felbatol) make scored tablets. This means they have an indented line in the middle where you can split the tablet. Ask your provider or pharmacist first if you need to split your tablet and how to do so safely if instructed to. If you have trouble swallowing the tablets, there's also an oral liquid of felbamate (Felbatol) available. You'll need a new prescription, so speak to your provider if you're interested in learning more about the oral liquid.
              Is felbamate (Felbatol) a benzodiazepine?
              No, felbamate (Felbatol) isn't a benzodiazepine (a group of medications that are sometimes used to treat seizures). It belongs to a different class of medications that works differently than benzodiazepines to treat seizures.
              Is felbamate (Felbatol) safe during pregnancy?
              There aren't enough studies to say whether taking felbamate (Felbatol) during pregnancy is safe for your baby. It's recommended to discuss with your provider about the risks and benefits of taking felbamate (Felbatol) while pregnant. Also let your provider know right away if you become pregnant while taking this medication. If you're currently pregnant and taking felbamate (Felbatol), you're encouraged to enroll in the North American Antiepileptic Drug (NAAED) Pregnancy Registry. This pregnancy registry monitors the safety of anti-seizure medications during pregnancy and helps researchers learn more about the risks. Enroll by visiting their website or calling 1-888-233-2334.
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              What are the risks and warnings for Felbamate (Felbatol)?

              Felbamate (Felbatol) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

              risk-warning

              Low blood cell counts (aplastic anemia)

              Felbamate (Felbatol) can cause aplastic anemia, a condition that causes dangerously low blood cell counts. This side effect is rare, but can be life-threatening because it makes you more likely to have serious infections and bleeding problems. It can happen after you've been taking felbamate (Felbatol) for many months, and it might take a while to go away after you stop taking this medication. Don't take felbamate (Felbatol) if you have a history of low blood cell counts. Your provider will order blood tests regularly to check your blood cell counts. Let your provider know right away if you're getting infections more often than usual, bruise or bleed more easily (or have red or purple spots on your body), or feel very tired or weak.

              risk-warning

              Liver failure

              Felbamate (Felbatol) can raise your risk of serious liver damage. This side effect is life-threatening and has required some people to get a liver transplant. Don't take this medication if you have a history of liver problems. Your provider will order blood tests regularly to check the health of your liver and make sure this doesn't become a serious problem. Let your provider know right away if you experience right-sided stomach pain, low appetite, dark urine, nausea, vomiting, or yellowing of the skin or eyes. You'll probably need to stop the medication if this happens.

              risk-warning

              Suicidal thoughts or behavior

              Antiepileptic (anti-seizure) medications like felbamate (Felbatol) can raise your risk of suicide or thoughts of suicide. Watch for new or worsening depression and any unusual changes in mood, especially during the first few months of taking this medication or if your dose changes. Report anything concerning to your provider. If you have thoughts of hurting yourself, call 911 or get medical attention right away.

              risk-warning

              Interactions with other antiepileptics

              Felbamate (Felbatol) can raise the levels of other common anti-seizure medications, such as phenytoin (Dilantin), valproic acid (Depakene), divalproex (Depakote), carbamazepine (Tegretol), and phenobarbital. If their levels in the body become too high, you're at a higher risk for side effects from these medications. On the other hand, some of these medications can also lower the levels of felbamate (Felbatol) in the body and cause felbamate (Felbatol) to not work as well. If you're already taking one of these other medications, your provider will lower their dose(s) when you start felbamate (Felbatol) to make sure your medications are safe for you to take. Let your provider and pharmacist know about all the medications you take so they can help you watch out for potentially dangerous interactions with felbamate (Felbatol).

              dosage

              Felbamate (Felbatol) dosage forms

              The average cost for 90 tablets of 600mg of Felbamate (Felbatol) is $71.24 with a free GoodRx coupon. This is 84.7% off the average retail price of $465.60.
              ml of oral suspension
              Ml of oral suspension
              DosageQuantityPrice as low asPrice per unit
              600mg/5ml300 ml$57.02$0.19
              tablet
              Tablet
              DosageQuantityPrice as low asPrice per unit
              400mg120 tablets$76.07$0.63
              600mg90 tablets$71.24$0.79

              Typical dosing for Felbamate (Felbatol)

              • Adults and children 14 years of age and older: The typical starting dose is 1,200 mg by mouth per day, split up into 3 or 4 doses. Your provider will raise your dose every 1 to 2 weeks as needed. The maximum dose is 3,600 mg total per day.

              • Children 2 to 14 years of age with Lennox-Gastaut syndrome: The dose will depend on your child's body weight. The typical starting dose is 15 mg/kg of body weight per day, split up into 3 or 4 doses. Your child's provider will raise the dose every week as needed. The maximum dose is 45 mg/kg of body weight total per day.

              Your dose might differ if you have kidney problems.

              interactions

              Interactions between Felbamate (Felbatol) and other drugs

              Felbamate (Felbatol) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Felbamate (Felbatol). Please note that only the generic name of each medication is listed below.

              Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

              Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

              Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

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              How much does Felbamate (Felbatol) cost?

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              contraindications-icon

              Felbamate (Felbatol) contraindications

              Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Felbamate (Felbatol) will not be safe for you to take.
              • History of low blood cell counts

              • History of liver problems

              alternatives

              What are alternatives to Felbamate (Felbatol)?

              There are a number of medications that your doctor can prescribe in place of Felbamate (Felbatol). Compare a few possible alternatives below.
              Felbamate (Felbatol)
              Used for:
              • Partial seizures in adults with epilepsy

              • Seizures linked to Lennox-Gastaut syndrome (LGS) in children - add-on treatment

              $57.02 Lowest GoodRx priceView Prices
              Used for:
              • Partial-onset seizures - add-on treatment

              $56.66 Lowest GoodRx priceView Prices
              Used for:
              $124.40 Lowest GoodRx priceView Prices
              images

              Felbamate (Felbatol) images

              Peach Oblong Wp 0321 - Felbamate 600mg Tablet
              This medicine is Peach, Oblong, Scored Tablet Imprinted With "Wp 0321".Peach Oblong Wp 0321 - Felbamate 600mg Tablet
              Yellow Oblong Fel 600 And Taro - Felbamate 600mg Tablet
              This medicine is Yellow, Oblong, Scored Tablet Imprinted With "Taro" And "Fel 600".Yellow Oblong Fel 600 And Taro - Felbamate 600mg Tablet
              Peach Oval An 735 - Felbamate 600mg Tablet
              This medicine is Peach, Oval, Scored Tablet Imprinted With "An 735".Peach Oval An 735 - Felbamate 600mg Tablet
              Pink Oblong 10 54 - Felbamate 600mg Tablet
              This medicine is Pink, Oblong, Scored Tablet Imprinted With "10 54".Pink Oblong 10 54 - Felbamate 600mg Tablet

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              References

              Best studies we found

              Amneal Pharmaceuticals of New York LLC. (2023). Felbamate tablet [package insert]. DailyMed.

              Centers for Disease Control and Prevention. (2020). Types of seizures.

              Colucci, R., et al. (1996). Effect of felbamate on the pharmacokinetics of lamotrigine. Journal of Clinical Pharmacology.

              GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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